Analysis Of Clinical Manifestation And Imaging Of Intracranial Venous Thrombosis Study

Objective:To investigate the cerebral venous thrombosis(cerebral venous, thr ombosis, CVT) of the clinical manifestations, imaging features, improve the unde rstanding of clinician to intracranial venous thrombosis, improve the rate of early diagnosis, reduce the misdiagnosis and mortality.Methods: The research adopts the method of retrospective study, eligible 19 intracranial venous system thrombosis patients in 1992 January to 2015 Februar y in the Second Affiliated Hospital of Dalian Medical University hospital for tre atment of patients, including male 7 cases, female 12 cases, aged 15-71 years ol d. Collected 19 cases of patients with gender, age, mode of onset, risk factors, c linical manifestations, thrombosis parts, imaging features and the method of treat ment, curative effect, short-term prognosis and other aspects to carry on the anal ysis summary.Results:1. the group of 19 cases of CVT patients with onset age between15-71 years old, one of the highest incidence of 21-40 years old, 52.6%, male 7cases, female 12 cases, the ratio of 1:1.7.2. 84.2% of the patients can be found and the risk factors, including infecti ous factors accounted for 42.1%, including upper respiratory tract(26.3%), pneu monia(5.3%), sinusitis(5.3%), purulent meningitis(5.3%), and non infectious fa ctors accounted for 68.4%, including anemia(26.3%), trauma(10.6%), diarrhea(5.3%), antiphospholipid antibody syndrome(5.3%), systemic lupus erythematosus(5.3%), connective tissue disease(5.3%), the pill(5.3%), hyperthyroidism(5.3%),malignant tumor(5.3%).3. The group study of acute and subacute onset accounted for 90.4% of pat ients, the clinical manifestations were headache(78.9%), nausea and vomiting(52.6%), limb paralysis(42.1%), symptomatic epilepsy(36.8%), disturbance of consci ousness(36.8%), neck strong(15.8%), sensory disturbance(15.8%), slurred speec h(15.8%), eyeball movement disorder(15.8%), diplopia(10.5%), psychiatric sym ptoms(5.3%).4.This group of researchers in patients with venous sinus in 31.6% brain C T examination of can directly display the high density sign, MRI examination in patients with venous sinus of 17.6% can directly display the abnormal signal. I ndirect imaging cerebral changes of brain tissue swelling in CT and MRI change s(36.8%), subarachnoid hemorrhage(26.3%),(26.3%) a new ischemic, hemorrha gic infarction patients(21.1%).5. Thrombophlebitis parts of this group of researchers in the transverse sinus(63.2%), followed by the superior sagittal sinus(42.1%)(31.6%), sigmoid sinus,inferior sagittal sinus, straight sinus(21.1%)(21.1%)(15.8%), cavernous sinus, i nternal jugular vein(10.5%), the great cerebral vein(5.3%). 84.2% of them invo lving 2 or more than 2 venous sinus, 15.8% involved single venous sinus. 1 cas es underwent MRI+MRV examination found no obvious abnormalities, after crani ocerebral DSA examination is abnormal.Conclusion:1. The proportion of men and women in the study group CVT patients have obvious difference, more women than men, the age of onset in y oung. Etiology is complicated, the group of non infection, the most common ane mia.2. Because of the etiology and clinical manifestations of diseased parts of di fferent complex and changeable, the group with acute and subacute onset, are co mmon clinical symptoms were headache, nausea, limb paralysis, symptomatic epil epsy, disturbance of consciousness, neck strong, sensory disturbance, slurred spee ch, eye movement disorder, diplopia and psychiatric symptoms.3.The thrombus site involved with the most common transverse sinus, follow ed by the superior sagittal sinus, sigmoid sinus, inferior sagittal sinus, straight si nus, cavernous sinus, internal jugular vein and great cerebral vein. For CT or M RI examination showed abnormal signals in cerebral edema, including common.4.MRI and MRV examination is the first choice method for diagnosis of C VT, DSA is the gold standard for diagnosis of CVT.5.Anticoagulant therapy is a safe and effective treatment method of CVT, an d clinical symptoms or anticoagulant therapy invalid can be added with thrombol ytic therapy.