The Effects Of Long Term Square Dance Movement On Elderly Women Serum GLP-1

Purpose This study selected the long-term stability of square dance exercise in nondiabetic elderly women as the research object, to explore whether aerobic exercise can improve glucose metabolism in the body, and the possible mechanism of aerobic exercise to prevent type 2 diabetes do further analysis. Around this theme, the incretin, glucagon like peptide-1(GLP-1) as the breakthrough point, to explore the effect of aerobic exercise on serum GLP-1 in elderly women, further analysis of the relationship between incretin and glucose metabolism, and provide a theoretical basis for the prevention and treatment of type 2 diabetes in the future.Method Randomly recruited subjects in the community of Shanghai city, aged 55-70 years old. Square dance movement group recruitment methods are as follows: the elderly women aged 55-70 years;in the perennial the square dance exercise, and exercise for more than 3 years; 5 times a week, and each time more than 40 minutes; the past 6 months weight remained relatively stable. Square dance movement group recruited 51 subjects. The control group recruitment methods are as follows: the elderly women aged 55-70 years; in addition to daily physical activity, do not do any sports exercise; the past 6 months weight remained relatively stable. The following two groups: BMI, 35kg/M2; exclusive criteria were diagnosed with type 1 diabetes or type 2 diabetes patients; psychological problems; suffering from severe heart disease and other cardiovascular diseases. The control group recruited 41 people.Results 1. Age, height, weight and BMI between the square dance group and the control group showed no significant difference(P > 0.05). 2. There are 32 individuals who had a normal fasting blood glucose, and the number who with impaired fasting glucose is 8 in the control group; and the corresponding figures in the square dance group are 16 and 35. There is no significant difference between the two groups(P > 0.05). 3. Compared with the control group, there was no significant difference in the level of leptin and blood lipid levels of four with square dance group(P > 0.05). 4. Compared with the control group,in the normal fasting blood glucose, serum GLP-1 of square dance exercise group had a higher level(P < 0.01);compared with the control group, within the scope of impaired fasting glucose, serum GLP-1 of square dance exercise group had a higher level(P < 0.01).Conclusion 1. There are no significant differences between the two groups with the level of blood glucose, triglyceride, Total Cholestreol, High Density Lipoprotein Cholestreol, Low density lipoprotein cholesterol, insulin, leptin. There is no difference with glucose metabolism between the two groups in this level. 2. Compared with the control group, the square dance exercise had a higher secretion of endogenous GLP-1, and a higher level of GLP-1 can improved glucose metabolism ability of the body. 3. Aerobic exercise is the main mode of motion in type 2 diabetes treatment and prevention, and aerobic exercise can’t change the blood glucose and insulin levels in the range of normal and impaired fasting glucose. But it can be enhance glucose metabolic capability by the increase of the secretion of endogenous GLP-1. Maybe this is the mechanism that aerobic exercise can prevent type 2 diabetes.