The Influence Of Ligustrum Lucidum Polysaccharide On Blood Deficiency Model Mice Blood Cell

Objective To observe the effects of Fructus Ligustri Lucidi polysaccharides on blood cell in mice blood deficiency model,Through the numerical detection of mice blood red blood cells, white blood cell, hemoglobin, platelet index.Aims to explore the the effect of deficiency type of Ligustrum lucidum polysaccharide on mice,For many clinical diseases especially to provide the experimental basis of ischemic disease medication.Methods This study selected Kunming mice, The male and female were randomly divided into five groups, Each group of 10 mice,there are as follows:(1) The physiological saline group(2) Blood deficiency model group(3)Ligustrum lucidum polysaccharide high dose group(4) Ligustrum lucidum polysaccharide in middle dose group(5)Ligustrum lucidum polysaccharide small dose group.Mouse tail vein blood, after dilute, Automatic counting of F-800 blood cell analyzer to text zhe WBC,RBC,HB,PLT ect ndicators. Administration of the first day Mouse tail vein blood0.5ml/10g, On zhe day of four,five,six,seven intraperitoneal injection cyclophosphamide (40mg/kg),7 days later Index detection. Do the statistical analysis will collect data, Laboratory data were compared between the five groups conclusion.Results 1. Effect on blood deficiency mice WBC, RBC:Compared with the saline group mice,Content decreased significantly of WB、RBC Model mice,Indicating a successful model(P< 0.01).Compared with the model group mice, Ligustrum lucidum polysaccharide high dose group,middle dose group of WBC、RBCcontent changes;2. Ligustrum lucidum polysaccharide, In improving the blood deficient mice, the content of RBC WBC.3. Effects of Fructus Ligustri Lucidi polysaccharides on blood deficiency mice Hb, Pit:Compared with the saline group mice, Changes of Hb, PLT content in blood cells of mice in the model group. Compared with the model group mice, The content changes of blood cells in mice of Ligustrum lucidum polysaccharide high dose group, medium dose group in Hb, PLT, Numerical so as to get the content of Ligustrum lucidum polysaccharide high, medium dose in mice model of blood cells in Hb, PLT, Shows that in a certain range of Ligustrum lucidum polysaccharide increased the number of blood cells in mice of Hb, PLT, WBC, RBC. Compared with the model group mice, The content of Polysaccharides from Fructus Ligustri Lucidi small doses can increase model mice blood cells WBC, RBC, but no significant difference.Conclusion Ligustrum lucidum polysaccharide can improve mouse WBC cells, RBC, Hb, PLT number of serum blood deficiency type, and there are the dose effect relationship in a certain range. As traditional Chinese medicine Fructus Ligustri Lucidi clinical experience with the dose of the different clinical blood deficiency diseases such as anemia and plays a certain role in blood, deficiency...