The Clinical Characteristic And Risk Of Capsule Incomplete And Retention In Crohn’s Disease

ObjectiveTo evaluate capsule endoscopy in terms of incomplete examinations and capsule retentions,to describe the characteristic of these events and to find risk factors for these events.MethodsThis retrospective and consecutive study includes data from204capsule enteroscopy examinations in patients with Crohn’s Disease,performed at the first hospital affiliated to zhejiang university medical school from June2003to April2014.ResultsThe frequency of complete examinations was56.9%. Male gender(OR=2.48, P=0.026), abdominal pain (OR=2.88,P=0.002),melena/bloody stools/OB+(OR=3.34, P=0.009)were risk factors for an incomplete examination.Capsule retention occurred in8.33%(n=17). The ratio of man and false was12:5.And the average age of these patients was42.2±16.2,and the average course of disease was52.5±46.6months. Of the seventeen cases of retained capsules,four patients chose to undergo surgery to remove the capsule for occurring symptoms of intestinal obstruction, spontaneous passage occurred in twelve patients after medical treatment, and one of the patients still have the capsule retained after16months of expectation. The longest capsule retained time in patients was four years.Risk factors for capsule retention was abdominal distention (OR=8.45,P=0.006).ConclusionsCapsule retention occurred in8.33%of patients with known CD,Male gender,abdominal pain,melena/bloody stools/OB+were risk factors for an incomplete examination.Abdominal distention was the risk factor for capsule retention. Twelve patients with capsule retention spontaneous passage occurred after medical treatment.And only four patients chose to under go surgery,but not emergency surgery, to remove the capsule for occurring symptoms of intestinal obstruction. So capsule endoscopy is considered a safe procedure, although obstructive symptoms and serious complications due to capsule retention can be found in patients with known CD.