The Comparison Of The Whole Protein Preparation With The Short Peptide Preparation In Patients With Severe Acute Pancreatitis In The Aspect Of Nutrition Support

Objective: To explore the early jejunum nutrition to give the whole nose preparations with a short peptide protein comparative analysis for the treatment of acute severe pancreatitisMethoths:To explore the early gastrointestinal function recovery with early enteral nutrition support therapy the clinical value of SAP.Selecting 50 cases of patients,who affect SAP and these patients are from ICU.These 50 cases were retrospectively analyzed into two groups, every group includes25 cases.One group is the whole protein preparation group(treatment group), the other group is short peptide preparation group(control group). The two groups were given respectively treatments.To compare nutrition support treatment group and the other group given 2 weeks nutritional support treatment,compare their he evaluation index, nutrition index, gastrointestinal function recovery, the infection indexes and prognostic indicators of change. Comparing analysis the different effect of early enteral nutrition open time,the early jejunum nutrition and the whole nasal catheter preparations with a short peptide protein on two groups.To explore the obvious difference of the prognosis of patients with SAP from whole protein to peptide nutrition preparation.Results : In terms of gastrointestinal functional recovery, intra-abdominal pressure determination of treatment group were significantly less than the control group, P < 0.05,there is statistical significance; Evaluation indicators,by the independent sample t-test APACHEII scores,and SOFE score, zhe value is P < 0.05,this indicates the two groups have obvious statistically significant difference; Nutritional risk score and computed tomography(CT) severity show no difference between the two indexes(P > 0.05); In termsof indicators of infection, the two groups have no evident difference on white blood cell count, three indicators of PCT, blood amylase content by independent sample t-test(P >0.05). Suggesting that the two methods have no significant differences on the targets of infection in patients. checked by Fisher’s exact probability method, the gastrointestinal complications of treatment group was obviously less than control group, P < 0.05, there is statistical significance; Examined by the Fisher’s exact probability method,it shows that the gastrointestinal complications of treatment group was obviously less than the control group(P < 0.01). But in treatment group and control group, mechanical complications and infection complications have no obvious difference between two groups. In terms of Nutrition indicators, the treatment group and control group albumin have no statistical significance(P > 0.05).Ferther more, acute phase ferritin in treatment group was obviously lower than the control group, the two groups have significant differences(P < 0.01).Conclusion:1. Given SAP patients early nasal jejunum, compared the whole protein preparation with short peptide nutrition preparation, the whole protein preparations can obviously reduce the incidence of gastrointestinal complications in patients with SAP, particularly in terms of intra-abdominal pressure measurement. Two kinds of preparation both can improve clinical symptoms, the protein preparation can promote the APACHEII scores,SOFE grading index returned to normal faster.2. Given SAP patients early nasal jejunum, compared the whole protein preparation groups with short peptide nutrition preparation group, both in terms of enteral nutrition on time, nutrition index of albumin, and albumin increase,two groups have no obvious differences. the case fatality rate in 28 days, prognostic indicators of CT evaluation and ICU length of hospital stay have no obvious differences.3. The whole proteins contain more glutamine.,it has more advantages than short peptide nutrition preparations. It has more advantages in the aspect of improving severe acute pancreatitis patients immunity, improving the body’s metabolism and nitrogen balance, promoting protein synthesis and increasing the total number of lymphocytes. The whole proteins can improve the prognosis of patients with severe acute pancreatitis better.