| Objective:To understand and analyze the relevant factors of children ’s acute intake poisoning,explore and compare the features of the non-drug poisoning group and the drug poisoning group in terms of various system damages, relevant abnormal lab indexes,treatment methods and economic losses, and to provide reliable basis for the clinical treatment, social publicity and family prevention.Method:The retrospective analysis method was used via selecting 117 children in-patients of acute intake poisoning in ICU of Dalian Children ’s Hospital from Jan., 2010 to Dec.,2013 to analyze the structure of the ages, genders, seasons, origins, poisoning reasons,poison types or other factors of those children, to compare such aspects as the damages to various systems, abnormal lab indexes, length of stays and hospitalization expenses of the non-drug poisoning group and the drug poisoning group, and to analyze the impacts on the prognosis of early or late clinic treatment and various treatment methods.Results:1. In those 117 cases of children patients with acute intake poisoning, most are infants accounting for 41.0% with preschools following at the percentage of 25.6%. The number of boys is more than girl with the proportion of 1.34:1. Most poisoning took place at home which accounts for 94.9%. Spring and summer were the seasons withhigh poisoning occurrence, with 33.3% and 29.1% respectively. 87.2% of the acute intake poisoning cases were accidental poisoning; accidental poisoning accounted for100% in the age group of 6 years old or younger, and non accidental poisoning accounted for 51.7% in the age group of older than 6 years old. When the causes of poisoning were compared between the two groups, the results were χ2=51.765,p<0.05.So there was significant difference with statistical significance. In the non drug poisoning group, most cases were caused by pesticides with the percentage of 63.6%. In the drug poisoning group, most cases were caused by psychiatric and psychopathic drugs with the percentage of 45.1%. For the comparison of the origins of the different groups, the results were χ2=4.980,p<0.05,so there was significant difference with statistical significance.2. The nerve system damage accounted for the highest percentage in the children ’s acute intake poisoning, which was 49.3%, and followed by the damage to the digestive system, which was 25.3%. Single system damage accounted for 60.0% and two system damages accounted for 26.3%. Electrolyte disturbance accounted for the most cases with the percentage of 23.3%, and leukocyte disorder accounted for 22.4%. As compared with the drug poisoning group, all p values are lower than 0.05 for the nerve system damages, leukocyte disorder, abnormal liver function, abnormal clotting time,abnormal acid-base balance of the non drug poisoning group, so there was significant difference with statistical significance.3. In the 117 cases of children patients with acute intake poisoning, 65.0% were cured and 3.4% were dead. When the impacts of the cure rate of the early treatment group was compared with the late treatment group, the results were χ2=10.835,p<0.05,so there was significant difference with statistical significance. When the cure rate of the non drug poisoning group is compared with the drug poisoning group, the result was p > 0.05, so there was no obvious statistical significance. When the cure rate of the blood purification treatment group was compared with the normal treatment group, the result was p>0.05, so there was no obvious statistical significance.4. The average length of stay of the acute intake poisoning was 5.30±5.27 days, andthe average hospitalization expenses were RMB 9,754.87±19,296.73 Yuan. When the average length of stay and hospitalization expenses of the non drug poisoning group were compared with the drug poisoning group, the result was p<0.05, so there was significant difference with statistical significance.Conclusions:1. 3/4 of the children patients with acute intake poisoning are infants and preschools of the age 1 to 6. There are more boys than girls patients, most poisoning accidents occurred at home and most cases occur in spring and summer. All the children under the age of 6 were accidental poisoning and half of the children above the age of 6were suicides. Most children from the countryside were non drug poisoning of pesticides while most children from the cities were drug poisoning from psychiatric and psychopathic drugs.2. After the occurrence of the children ’s acute intake poisoning, half of the children got a single system affected, 1/4 of the children got two systems affected. In most cases the nerve system and digestive system were affected. 4/5 of the children have the abnormal lab indexes with most cases of electrolyte disturbance and leukocyte disorder.The leukocyte disorder, abnormal liver function, abnormal clotting time, acid-base imbalance or other damages to lab indexes of the non drug poisoning group were all higher than the drug poisoning group, but the nerve system damages were lower than the drug poisoning group.3. Nearly 2/3 of the children of acute intake poisoning were cured after positive clinical treatment, but nearly 1/20 of the patients died. The timing of the treatment is key to the clinical recovery so it is crucial to treat within 4 hours of the poisoning. The cure rate of early treatment group was apparently higher than the late treatment group,while there was no difference in the impacts of the various poisoning groups and treatment methods on the clinical outcome.4. The average length of stay of the acute intake poisoning was 5.30±5.27 days, and the average hospitalization expenses were RMB 9,754.87±19,296.73 Yuan. The direct economic losses such as the length of stay and the hospitalization expenses of the nondrug poisoning group were significantly higher than those of the drug poisoning group. |
PDF Full Text Request