Transcranial Sonography For The Diagnosis Of Parkinson’s Disease

Background and Objective：The diagnosis of Parkinson’s disease at home and abroad for now, mainlythrough clinical symptoms to diagnosis, there is no means of checking can be an aidearly diagnosis of the disease. This study is intended for patients with Parkinsonpassing cranial ultrasonography, This study is aim at analysising the echo ofquantitative analysis for the patient with Parkinson’s disease, which is to assist indiagnosising in the early of Parkinson’s disease, which is in order to improve thequality of life of patients in the early of the disease.Patient and Method：The patient was collected from May2013to December2013in our hospitalclinic patients with Parkinson’s disease and Parkinson’s disease, a total of72(39males,33females),age from48years to79years, mean age(60.6±6.8) years,duration of0.5-10.3years, of which five (four female, one male) bilateral temporalwindow penetrate poor,7(4female,3male) due to poor penetration of unilateraltemporal window, statistical evaluation was not involved. All patients in theneurology clinic after diagnosis by neurology specialists, re-parenchymal ultrasound.Involved in60patients was assessed, Diagnosed with Parkinson’s disease for32patients (20male,12female),28patients with Parkinson’s disease (15male,13female), Examination underwent ultrasound examination of the brain parenchymapatient’s condition did not know.Select the same period70volunteers, aged from40to80years, mean age is56.2±8.4years, of which12volunteers due to poor penetration of the temporal windowwithout participation statistically evaluated. Experimental group and the healthycontrol group, age and gender composition of no statistical difference.Result：Gray values from the substantia nigra and the surrounding brain tissue gray value point of view: in color mode and two-dimensional model, PD patients wassignificantly higher than the substantia nigra gray gray values surrounding brain tissue,there are significant differences, P <0.05, while patients with Parkinson’s syndromeand normal control group were in color mode and two-dimensional model, thesubstantia nigra and the gray value without the surrounding brain tissue gray valuesignificant difference, P>0.05.From nigra gray values for the identification of the statistical aspects of thedisease: PD group compared with the control group, a significant difference in thecolor mode and two-dimensional model nigra gray, P <0.05. PD group compared withpatients with Parkinson’s syndrome, in color mode and two-dimensional pattern ofgray nigra significant difference, P <0.05. Parkinson’s syndrome patients and normalcontrol group no gray value nigra significant difference, P>0.05.From the third ventricle width for disease identification statistical significanceaspects: PD group of patients and Parkinson’s syndrome and normal control groupwere not statistically different.Conduct：The echo of the substantia nigra (SN) in patients with Parkinson’s disease (PD)group was significantly higher than the echo in Parkinson’s syndrome patients andnormal control group. Transcranial color Doppler ultrasound for the diagnosis ofParkinson’s disease is meaningful.