The Clinical Research Of87Patients With Cervical Cancer In Stage â…¡A2

Purpose: To provide reference for alternating clinical therapeuticregimen via a contrastive analysis on the effects and prognosis differenceof various treatments for cervical cancer type IIA2.Method:reviewand analyzethe87casesof cervical cancer typeIIA2that our hospital has cured between2009and2012.Classify all the treatingmethods into following groups: initial operation group (group A)neoadjuvant chemotherapy＋surgery (group B), pure concurrent radiochemotherapy (group C).Compare in groups the clinical data of all these87cases and analyze them via Chi-square test, T-test and survival analysiswhich are adopted from statistical methods.Results：1. Contrasting the intraoperative conditions of A and B:no statisticalsignificance lies in the difference between respective average operationtime;The relatively lower amount of bleeding in Group B shows astatistical significance, while the number of lymph node excision inA&Bdoesn`t.2.ContrastingthepostoperativecomplicationinAanB:thedifferencein occurrence rate of each group shows no statistical significance. Group Bprocesses a lower occurrence rate in lymphocele and postoperativeinfection, which has a statistical significance. And the difference amongoccurrence rate of uroschesis, postoperative thrombus of lower extremityveins and incisal edge contribute nothing to statistical significance. 3. Contrasting the pathologic conditions of group A&B: values oflymphonodus positive rate, vessel infiltration and deep muscular layerinfiltration in Group A are higher than group B, which has a statisticalsignificance. The positive diference of incisal edge has no statisticalsignificance.4. Contrasting the3-year overall survival rate among group A.B&C,there`snostatisticalsignificance.interms ofprogression-freesurvival rate,Group C`performance is the highest of the three, which has a statisticalsignificance. The difference between A and B on this has no statisticalsignificance.Conclusion：According to the results, Conclusions for cervical cancer type IIA2treatments are as following:1. Compared to initial operation, neoadjuvant chemotherapy causeslower amount of bleeding,and decreases postoperative infection and thelymphocele rate.2. Compared to initial operation, neoadjuvant chemotherapydecreases lymph node positive rate, vessel infiltration and deep muscularlayer infiltration-factors that affect prognosis.3. These three methods make no difference in the impact on overallsurvival rate, yet concurrent radio chemotherapy can extend the durationof progression-free survival.4. Each method has pros and cons that individualized treatments are essential in clinical practice.