The Clinical Studies Of Adjusting Sleep Stability In Patients With Primary Insomnia By Acupuncture

Objective:The issue from the perspective of sleep stability, observing the effects on sleep microstructure of primary insomnia by acupuncture, revealing the neurophysiological basis of acupuncture treatment of patients with primary insomnia.Methods:According to the diagnostic criteria of DSM-Ⅳ, we collected patients with primary insomnia as the patient group, the normal population as the control group.Using acupuncture treatment method,patients with primary insomnia group (PI) need finish two courses of acupuncture treatment, a total of20times. The control group did not offer any treatment. The scale of the Pittsburgh Sleep Quality Index (PSQI) were used to measure subjectively the sleep quality,through the whole night sleep monitoring (PSG), and the use of cyclic alternating pattern analysis method (CAP) assessment objectively the sleep quality. Before and after acupuncture treatment, patients with primary insomnia group undergo subjective and objective sleep quality testing once each and control group undergo subjective and objective sleep quality assessment when join the study.Results:①Pittsburgh Sleep Quality Index Scale of each item:sleep quality (SQ), sleep time (FST), sleep time (ST), sleep efficiency (SE), sleep disorders (SD), sedative-hypnotic medicine (SM), daytime dysfunction (DD) and total score, primary insomnia group were higher than control group(P<0.05), compared before and after acupuncture treatment effect in patients with primary insomnia, after patients with primary insomnia group (PI) undergo acupuncture treatment, these are lower than patients with primary insomnia group before undergo acupuncture treatment (P<0.05);②Traditional sleep analysis parameters:total sleep time (TST), sleep efficiency (SE), NREM duration time(NRT), REM ratio (REM%), primary insomnia group were lower than control group (P<0.05),compared before and after acupuncture treatment effect in patients with primary insomnia, after patients with primary insomnia group undergo acupuncture treatment, these are higher than patients with primary insomnia group before undergo acupuncture treatment (P<0.05),The opposite was for the REM duration time(RT), REM latency (REML)(P <0.05);③EEG arousal parameters:number of awakenings (TA), wake time (ATA), arousal index (AI), primary insomnia group were higher than control group(P<0.05), compared before and after acupuncture treatment effect in patients with primary insomnia, after patients with primary insomnia group undergo acupuncture treatment, these are lower than patients with primary insomnia group before undergo acupuncture treatment (P<0.05);④The cyclic alternating pattern parameters:CAP rate, CAP total occurrence, CAP number sequence, CAP sequence duration, CAP number of cycles, CAP cycle duration, Al subtype total, A2subtype total total A3subtype, the primary insomnia group were higher than the normal control group (P<0.05), compared before and after acupuncture treatment effect in patients with primary insomnia, after patients with primary insomnia group undergo acupuncture treatment, these are lower than patients with primary insomnia group (PI) before undergo acupuncture treatment (P<0.05).Conclusion:1. Sleep quality quality can be promoted effectively by acupuncture in patents with primary insomnia.2.Acupuncture is able to improve sleep quality in patients with primary is related to changing its microstructure disordered sleep and enhance the stability of sleep.