An Analysis On Related Psychological And Social Factors Of Psychosis Risk Syndrome

Objective:To investage psychological and social factors of psychosis risk syndrome.Methods:Collected254cases(age16-35) first-degree relatives of schizophreniapatients were screening by Criteria of Prodromal Syndromes(COPS),16patients withpsychosis risk syndrome (patients group) and32first-degree relatives of schizophreniapatients with negatie results of COPS(controls group) were selected.The patient’sclinical symptoms were assessed by Scale of Prodromal Symptoms(SOPS).NeUrocogn-itive tests included Trail Making Test-A(TMT-A),Schizophrenia simple cognitiveassessment: symbol coding,Hopkins Verbal Learning Test-Revised(HVLT-R),Brief Vis-uo spatial Memory Test-revised(BVMT-R),Stroop Color and Word Test(CWT) andContinuous Performance Test-Identical Pair(CPT-IP).Social psychology tests includedChildhood Trauma Questionnaire(CTQ-SF),Family Adaptability and CohesionScales(FACES II-CV),Adolescents Self-Rating Life Events Checklist(ASLEC),Perceiv-ed Social Support Scale(PSSS),Global Assessment of Functioning scale(GAF),Rosenb-erg Self-Esteem Scale(SES) and Coping Style Questionaire(CSQ).The data wascompared between two groups and correlation analysis was applied by using StatisticPackage for Social Science19.0(SPSS19.0).Results:(1)The prevalence of psychosis risk syndrome in first-degree relatives ofschizophrenia patients with age16-35was62.99‰.(2)Patients,attachment test time waslonger than controls(t=4.169,P<0.001),other test performances were lower thancontrols(P<0.05or P<0.01);Compared with the normol controls,the patients,cognitiveimpairment was moderate.There was a significantly negative correlation betweenperformances of TMT-A and GAF(r=-0.532,P<0.01),Significantly positive correlationbetween GAF and symbol coding(r=0.624,P<0.01),HVLT-R(T1:r=0.578,P<0.05),aswell as BVMT-R(T3:r=0.498,P<0.05).(3)Social psychology:The performances of emotional abuse(t=3.890,P<0.001),sexual abuse(t=2.859,P<0.01),emotional neglect(t=3.087,P<0.01)and total score of CTQ-S (t=4.455,P<0.001)in patients were significantlyhigher than those in the control group.There were significantly positive correlationsbetween positive symptoms and physical abuse(r=0.515,P<0.05),emotional neglect(r=0.563,P<0.05)or the total CTQ-SF score(r=0.601,P<0.05).The total score of SOPS waspositively correlated with physical negative symoptom(r=0.597,P<0.05).Patients ofpsychosis risk syndrome group were lower than the controls on actual familyadaptability(t=-2.398,P<0.05) and cohesion(t=-2.113,P<0.05).The actual familycohesion was positively correlated with GAF(r=0.528,P<0.01),as well as the actualadaptability and positive symptoms(r=0.585,P<0.05).The patients,interpersonalrelationship(t=3.448,P<0.01),academic stress(t=3.218,P<0.01),loss(t=3.278,P<0.05),he-alth adaptation(t=-2.718,P<0.05) and total score(t=-2.398,P<0.05) were higher than thecontrols,but there was no significant differences in the performances of penaltyfactor(t=1.883,P=0.066) and other factors(t=1.954,P=0.057).The penalty score wasnegatively correlated with positive symptom(r=-0.548,P<0.05).There was positivelyrelated between the total score of SOPS and loss(r=0.512,P<0.05),and health adaptation(r=0.618,P<0.05).The performances of patients were lower than the control group onfamily support(t=-4.577,P<0.001),other support(t=-2.024,P<0.05) and total score ofPSSS(t=-3.135,P<0.01).Patients,self-esteem(t=-4.02,P<0.001) and problem solving(t=-6.711,P<0.001) were lower,Self-accusation(t=2.095,P<0.05) and rationalization factor(t=2.095,P<0.05) were higher.The difference of two group’s help(t=-0.046,P=0.964),fa-ntasy(t=1.505,P=0.139) and backoff(t=1.572,P=0.123) showed no statistical significan-ce.The level of self-esteem was negatively correlated with positive symptoms(r=-0.653,P<0.01),and positively correlated with negative symptoms(r=0.634,P<0.01).The scoresof family support(r=0.613,P<0.05),friend support(r=0.611,P<0.05) and the totalscore(r=0.589,P<0.05) were all positively correlated with GAF.Patients,problemsolving and positive symptomswere negatively correlated(r=-0.499,P<0.05),significantpositive correlation were observed between retreat and negative symptoms(r=0.648,P<0.01),the total score of SOPS(r=0.558,P<0.05),and reasonable positively correlated withpositive symptom(r=0.649,P<0.01).Conclusions:(1)The prevalence of psychosis risk syndrome in first-degree relatives ofschizophrenia patients with age16-35is62.99‰.(2)Psychosis risk syndrome patients have a wide range of cognitive impairment, such as information processing speed,wordlearning,visual learning,working memory and attention/alertness.The degree ofcognitive impairment has inner link with social functions.(3)The psychiatric risksyndrome patients have higher early abuse experiences.The level of physical abuse,emotional neglect and the total abuse relate to the severity of positive symptoms.Theperformance of psychiatric risk syndrome patients are relatively lower on actual familycohesion and adaptability.There is a relationship between family closeness and socialfunction,as well as adaptability and positive symptoms.Patients have more negative lifeevents, and the negative life events associate with severity of mental symptoms.Thepatients,performance of social support, self-esteem and positive coping level are lower,the level of self-esteem and coping measures relate to mental symptoms, social supportassociated with social function.