The Ratio Of Oral Antibiotics, Compliance And Efficacy For Non-severe Community-acquired Pneumonia In Children

Objective: To investigate ratio of oral antibiotics and efficacy for non-severecommunity-acquired pneumonia in children, and analyze the factors on compliance, andseek countermeasure.Methods:(1)From January to June this year, ratio of oral antibiotics for outpatientswas investigated and157parents whose children had a fever or cough voluntarilyparticipated the questionnaire survey, and the compliance were analyzed.(2)Seventy-seven patients with non-severe community-acquired pneumonia who wererandomly chosen from our hospital were divided into oral group (35cases, among them30cases by the way of oral antibiotics during the whole course and the rest of them bythe way of oral and intravenous antibiotics) and intravenous group (42cases) accordingto the way of antibiotics. And the efficacy of all patients with antibiotics wasretrospectively analyzed. There were no statistically significant differences in meanages were [(2.40±1.41) years old vs (2.50±1.52) years old)] between the oral groupduring the whole course and intravenous group(P＞0.05), and as well as the ratios ofmale to female (21/9vs24/18).Results:(1) There were only23.21percent (1288/5550) patients with oralantibiotics therapy in outpatients. And there were76.79percent (4262/5550) patientswith intravenous antibiotics.(2) One hundred and thirty-eight parents (87.90%)considered that intravenous antibiotics therapy was better than oral antibiotics therapy.Parents asked pediatricians to use intravenous antibiotics therapy for their childrenwhen children had a fever only one-day (40.13%) or two-day (31.21%). And there were59.87%early patients who were advised to use intravenous antibiotics therapy bypediatricians.(3) There were85.71percent (30/35) patients with oral antibiotics duringthe whole course.(4) There were no statistically significant differences in duration timefor alleviated cough [(5.08±1.26)d vs (4.67±1.99)d], duration time for completely disappearing [(9.95±1.43)d vs (9.28±1.65)d] and courses of antibiotics[(7.81±1.57)d vs(7.08±1.54)d] between oral group and intravenous group(P＞0.05). The duration timefor returning to normal body temperature in oral group during the whole course[(2.69±0.48)d] was higher than that in intravenous group [(2.11±0.79)d](P<0.05), andthe duration time for disappeared lung rale in the former [(6.53±1.74)d] was higher thanthat in the latter [(5.44±2.06)d](P<0.05).The patient’s conditions in intravenous groupwere recorded by attending pediatricians every day. The patient’s conditions in oralgroup during the whole course were recorded by returning visit at a certain interval(2~7d).(5)The ratio of cure was100percent in oral group during the whole course andintravenous group, respectively.Conclusion:(1) In this study，there is a low ratio of oral antibiotics.(2) Thefactors for the effect of oral antibiotics on compliance are mainly due to parents’misunderstanding the intravenous antibiotics.(3) It should enforce to recognize to thevalue of oral antibiotics by communication between pediatricians and patients, andimprove pediatricians’ knowledge for rational antibiotics use, which can remarkablyimprove the compliance and the ratio of oral antibiotics. Efficacy of oral antibiotics andintravenous antibiotics were no significant differences.