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Clinical Studies In Elderly Patients With Diastolic Heart Failure With Nicorandil Treatment

Posted on:2015-01-04Degree:MasterType:Thesis
Country:ChinaCandidate:L YuanFull Text:PDF
GTID:2284330467973462Subject:Traditional Chinese Medicine
Abstract/Summary:PDF Full Text Request
Objective To observe the clinical study of oral nicorandil in elderly patients with diastolic heart failure.Methods Choose our hospital and diagnosed300patients with diastolic heart failure, All male, Aged70to85years,The patients were randomly divided into a control group,150cases) and nicorandil group (150cases).Patients in the control group were given conventional diu left atrial volume index (LAVD), mitral peak early diastolic velocity (EPFV), mitral peak late diastolic velocity (APFV) and E/A,4Detection of N-terminal brain natriuretic peptide (NT-pro BNP) index changes.Results:Nicorandil before treatment and control groups in general there was no significant difference (P>0.05), given oral medication Hou Nike to Seoul group ultrasound showed impr retic,β3-blockers and angiotensin-converting enzyme inhibitors, nicorandil group on the basis of taking these medications on to nicorandil (5mg3/day), once90days. Respectively, in a month,, three months to monitorEchocardiographic measurements ofoved heart function, BNP levels than the control group (u=2.475, t-2.0610, p<0.05), the difference was statistically significantConclusion:Diastolic heart failure in elderly patients with oral nicorandil can significantly improve heart failure indicators...
Keywords/Search Tags:Nicorandil, elderly, diastolic heart failure
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