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To Evaluate The Treatment Of Malignant Ovarian Tumors And Fertility-preserving Treatment

Posted on:2015-07-20Degree:MasterType:Thesis
Country:ChinaCandidate:S F LiFull Text:PDF
GTID:2284330467969488Subject:Gynecology
Abstract/Summary:PDF Full Text Request
Objective:To research the clinical characteristics, histological types,treatment,operation methods and chemotherapy after the operation and thesignificance of reserving reproductive function and ovarian function in femalepatients with the malignant tumor of ovaries and the impact it had onPrognosis. Methods:Through the retrospective analysis and summarizingof the case histories in female patients, which all from maternal and childhealth hospital of Lianyungang City, Jiangsu province in2003-2013. And thesystematic analysis of the clinical characteristics, treatment methods,pathology nature of tumor, stages, operation methods, adjuvant chemotherapy,paragnosis then came the data. The data was evaluated by SPSSl6.0analysis software. And the difference had statistical significance whenP<0.05.Results:During the last10years, there were54cases of the patientswith ovarian malignant tumors in our hospital. The youngest was16years oldand the oldest was67years old. The average age was31.2years old,and themedian age was24.6years old. Among the patients, there were7cases ofborderline ovarian tumors,15cases of epithelial ovarian cancer,5cases ofovarian gonadal sex cord stromaltumor,20cases of ovarian germ cell tumors,and7cases of metastatic tumors. The patients lack of specificity clinicalmanifestations. Main shows abdominal distension, abdominal pain andabdominal mass. A few patients have the menstrual symptoms. Most of the clinical stage is earlier:there are26patients in Stage I, accounting for48percent;6patients in Stage II, accounting for11percent;13patients in StageⅢ, accounting for24percent;and9patients in Stage IV,accounting for16percent. There is a direct correlation between ovarian malignant tumor’sprognosis and clinical stages. The clinical stages are the related factorsaffecting the prognosis. Conclusions:For patients,the germ cell tumor is themost common type of the malignant ovarian tumor.Because the clinicalmanifestations of the malignant ovarian tumor are nonspecific and lackingearly diagnostic methods, we should attach importance to and strengthen thegynecology imaging examination.For some young female patients withovarian germ-cell malignant tumors,no matter in which clinical stage,reproductive function need to be kept for improving the life quality.However,late follow-up is very necessary. For the patients with epithelial malignanttumor patients including IA、IC stage and GI-G2period, who has fertilityrequirements,reproductive function can be kept,but must be long-term closefollow-up. In the study, there is no lack of some patients in phase I and phaseII, who achieving a successful pregnancy, but lack of a large sample ofclinical proofs. It has significance for the patients to take theexpectant treatment, which keeping the ovary and reproductive function to thegreatest extent. Management of women diagnosed with gynecologic cancershould be made an individualized treatment, with the risk of conservativetherapy balanced against the disadvantages of more radical treatment.
Keywords/Search Tags:Ovary, malignant tumor, Reproduction
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