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Clinical Analysis Of Vertebrobasilar Dolichoectasia Relationship With Stroke

Posted on:2015-10-28Degree:MasterType:Thesis
Country:ChinaCandidate:Y B GeFull Text:PDF
GTID:2284330467470652Subject:Neurology
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Background and objective:Vertebrobasilar dolichoectasia is a special kind of variability and cerebrovascular disease that still in the stage of clinical research and exploration. With the development of medical imaging, people gradually increase awareness of the disease. The purpose of this study was to analyze the vertebrobasilar dolichoectasia extend imaging, and the relationship between stroke and major clinical data provide evidence for early diagnosis and early treatment.Methods:All objects were selected from the stroke patients at the neurology department of the Second Affiliated Hospital, Zhejiang University School of Medicine from December2012to May2013. Diagnosed by imaging, diagnostic criteria are in line with the Fourth National cerebrovascular disease, excluding the brain parenchyma and other organic diseases.We noted clinical data (age, gender, smoking and alcohol, hypertension, diabetes, hyperlipidemia, obesity, coronary heart disease, previous history of stroke).By receiving intracranial computed tomography, magnetic resonance imaging or magnetic resonance angiography, imagine (specific lesions,vertebral basilar artery diameter size,height of bifurcation,lateral displacement) in VBD judgement.All patients were divided in VBD or non-VBD. VBD was diagnosed by board certified neuroradiologists, applying the computed tomography criteria of Smoker et al and magnetic resonance imaging criteria of Giang et al, as magnetic resonance angiography criteria of Ubogu et al.All data was analysised by SPSS17.0software.Results:1. A total of772cases,558cases of cerebral infarction,214cases of cerebral hemorrhage. VBD45patients (5.8%) over the same period of acute stroke patients, including33cases of cerebral infarction in patients with VBD, accounting for5.9%of cases of cerebral infarction.12patients of cerebral hemorrhage with VBD, accounting for5.6%of cases of cerebral hemorrhage.2.45cases of VBD patients,727cases of patients with non-VBD, compared with the clinical data of two groups, the two groups found that men (χ2=3.875, P<0.05), obesity (χ2=5.243, P<0.05), smoking history (χ2=4.213, P<0.05) were significantly different, while age (t=1.245, P>0.05), hypertension (χ2=0.274, P>0.05), diabetes (χ2=0.966, P>0.05), high hyperlipidemia (χ2=0.974, P>0.05), coronary heart disease (χ2=0.184, P>0.05), history of stroke (χ2=0.012, P>0.05) was not statistically different.3.45cases of VBD patients, according to imaging,33cases of cerebral infarction in patients with basilar artery diameter VBD average of5.04±0.27mm, the average diameter of the vertebral artery was4.55±0.16mm, the height of the basilar artery bifurcation ratings averaged1.45±0.56, the lateral displacement of the basilar artery rating average1.33±0.48, and12cases of cerebral hemorrhage in patients with basilar artery diameter average of5.13±1.00mm, the average diameter of the vertebral artery4.48±0.40mm, the height of the basilar artery bifurcation ratings averaged2.08±0.51, the lateral displacement of the basilar artery rating average1.25±0.45. VBD basilar artery bifurcation height in patients with cerebral hemorrhage group was obviously higher than that of the cerebral infarction group (P<0.05).4. VBD with cerebral infarction group was closely associated with lacunar infarction and brain stem infarction, VBD with cerebral hemorrhage group was closely related to brain stem hemorrhage.Clinical symptoms were related to infarction or bleeding site.Conclusion:1.Incidence of VBD in cerebral infarction and cerebral hemorrhage is little difference.2. VBD is closely related to the occurrence of stroke in men, smoking and obesity.3. Basilar artery bifurcation height is closely related to the occurrence of cerebral hemorrhage in VBD.4. A variety of imaging methods can improve the rate of clinical diagnosis of VBD.
Keywords/Search Tags:Vertebrobasilar dolichoectasia(VBD), Stroke, vascular risk factors, imaging
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