Evaluation Of Left Ventricular Function In Coronary Heart Disease Without Visusal Segmental Wall Motion Abnormalities By4-Dimensional Left Ventricular Semi-Automated Quantification Tool

Objective:To investigate the value of4-dimensional left ventricular semi-automated quantification tool (4DLVQ) evaluating left ventricular function in coronary heart disease without visual segmental wall motion abnormalities.Methods:Sixty-two patients with coronary heart disease (CHD) which without visual segmental wall motion abnormalities were studied, forty-eight cases of healthy volunteers as a control. Biplane Simpson’s method left ventricular ejection fraction (2D-LVEF) and left ventricular long axis of the global longitudinal peak strain (GLPS) were measured respectively using M-mode echocardiography and real-time three planar automated functional imaging (AFI). Meanwhile, the four-dimensional left ventricular ejection fraction (4D-LVEF) and left ventricular end-systolic global longitudinal strain (GLS), global circumferential strain (GCS), global area strain (GAS), global radial strain (GRS) were measured by the4D imaging. Results:1、In the CHD group,4D-LVEDV increased significantly (P<0.01), 4D-LVEF and GLPS, GLS, GCS, GAS, GRS of CHD were lower compared to those of the control group (P<0.01).2, GLPS, GLS, GCS, GAS, GRS of CHD had good correlation with4D-LVEF, and GAS had the highest correlation (r=-0.831), GCS、GLS、 GRS lower (r=-0.815; r=-0.758; r=0.708), GLPS the lowest (r=-0.705).3、LVEDV, LVESV,4D-LVEF, GLS, GCS, GAS, GRS measured by4DLVQ had good repeatability.Conclusion:The left ventricular global ejection fraction and myocardial strain measured by4DLVQ are sensitive, feasible and reproducible parameters in assessing LV function of CHD without visual segmental wall motion abnormalities, especially GAS.