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Clinical Study Of The Oral Squamous Cell Carcinoma With The Clinically Olymph Node-negative

Posted on:2015-07-27Degree:MasterType:Thesis
Country:ChinaCandidate:S Z HanFull Text:PDF
GTID:2284330467455544Subject:Oncology
Abstract/Summary:PDF Full Text Request
Objective:By cN0oral squamous cell carcinoma retrospective analysis of clinical data to explore thecervical lymph node-negative (clinical lymph node-negative cN0) of oral squamous cell carcinoma (oralsquamous cell carcinoma, OSCC) law of occult metastases in patients with cervical lymph node and relatedfactors,to determine whether treatment of cervical lymph node row over the same period.Methods:First Affiliated Hospital of Shihezi University in July2008to July2013to accept clinical andpathological data of85cases of cervical lymph node dissection in patients with oral squamous cellcarcinoma cN0, retrospective analysis of occult neck metastasis and age, sex, disease duration, location,tumor size and staging relevance explore choose cN0neck metastasis in oral squamous cell carcinoma andclinical treatment methods.Data were processed using SPSS software and chi-square test correlation; definethe existence of significant differences P <0.05.Result:85cases of patients with squamous cell carcinoma, the oral cavity cN0total occult metastasis was28.34%(24/85). In this study,the incidence rate of occult metastases were higher in the end: the end ofsquamous cell carcinoma of the mouth, the retromolar squamous cell carcinoma, squamous cell carcinomaof the cheek, gums,squamous cell carcinoma,squamous cell carcinoma of the lip,tongue squamous cellcarcinoma.cN0lymph node metastasis in patients with oral squamous cell carcinoma and gender,anatomical site no statistically significant (P>0.05), with age,tumor size,pathologic stage and growthpattern exists a significant correlation(P <0.05).Conclusion:cN0oral squamous cell carcinoma of the neck of occult metastases with age, tumor size,pathologic stage,there is a significant growth pattern correlated with sex,disease site no significantcorrelation.The younger the patient, the higher the occult cervical lymph node metastasis rate,so the youngpatients need to line the cervical lymph node dissection. Well-differentiated squamous cell carcinomacompared with poorly differentiated squamous cell carcinoma of occult lymph node metastasis rate of itsneck, well-differentiated squamous cell carcinoma of the oral cavity other than the need to deal with theenthusiasm of cervical lymph nodes. Tumor volume, the higher its rate of occult metastases, and whenmaximum tumor diameter> When1cm, the need to actively deal with the neck line. Invasive squamous cellcarcinoma compared with ulceration and exogenous rate of occult metastases of squamous cell carcinomaof the line corresponding to such patients need to actively deal with neck dissection.
Keywords/Search Tags:Oral squamous cell carcinoma, occult metastases, neck dissection
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