| According to the historical data of iodine deficiency disorders (IDD), in Tibet with low environment iodine and iodized salt coverage, there was hardly epidemiology of IDD in pastoral areas, meanwhile agricultural areas around had serious IDD epidemiology. From existing data, it could be reasons inferred as follows:(1) The environment iodine and the level of urinary iodine (UI) of people in Tibet were low;(2) There was no epidemiology of endemic goiter or cretinism in pastoral areas, but endemic goiter prevailed in agricultural areas;(3) There were different dietary patterns between the two areas, especially the intake of protein from animal products. Previous research has shown that the main factor of goiter prevalence may be associated with the dietary intake of animal foods. Therefore, the author proposed the hypothesis:whether the differences of the prevalence between the two places is caused due to differences in animal food intake; whether the thyroid hormone contained in animal food (dry beef and dairy) which directly absorbed by the body, caused goiter prevalence differences in agricultural and pastoral areas of Tibet; whether pastoral areas had other trace elements such as selenium and iron in the diet, to ease the goiter condition.PurposesTo explore the detection of thyroid hormone in the dried beef. To analyze the relationship between the intake of thyroid hormone and the prevalent of goiter in agricultural and pastoral areas of Tibet. To find out that the high intake of animal protein in pastoral area is whether the reason of low goiter morbidity. To explain the possible reasons of lower iodine intake but no goiter prevalence and learn more about the relationship between dietary pattern and IDD.MethodsIn pastoral County named Naqu and agricultural County named Zhanang,100households with target population of Tibetan families lived for more than two years were selected respectively. Three consecutive days of dietary survey with24-hour history recalls and food frequency questionnaires were filled by the investigators through question-and-answer format with the respondents. Meat consumption of per household per year and per capita per day, as well as selenium and iron intake per day, etc. were calculated. The100g dried beef and30ml fresh milk of each household were collected for testing thyroid hormone content, and daily intake dosage per capita through food were calculated.ResultsThe pastoral household consumption of red meat and dairy products per year was3times as the agricultural household. There was no statistically significance of vegetables and eggs between the two counties; cereals, meat and dairy intake per capita in pastoral county was significantly higher than agricultural county.In the pastoral county and the agricultural county the dried beef content of thyroid hormone were62.63μg/kg and25.05μg/kg, with no statistically significance (z=6.575, p<0.05); The dried beef intake in the pastoral county was80.91g, which was significantly higher than that of agricultural county (46.24g). The herdsman obtained thyroid hormone4.98μg daily per capita through dried beef, and the peasant obtain1.09μg, with statistically significance (z=9.729, p<0.05). By gender stratification, dried beef consumption and the amount of thyroid hormone of both men and women in the pastoral county were significantly higher than those in agricultural county. The content of thyroid hormone in milk samples in pastoral county (13.5μg/kg) was significantly more than it in agricultural county (4.13μg/kg)(z=-7.167, p<0.05); thyroid hormone volume obtained of pastoral and agricultural residents per capita daily through milk were3.74μg and0.93μg respectively, and the difference was statistically significant. The intake of dairy and the thyroid hormone volume in pastoral county, were significantly higher than those in agricultural county. And those also had statistical significance between the two counties divided the files by different genders.Total intake of thyroid hormone through animal protein in the pastoral county was significantly higher than agriculture county (p<0.05). It showed that the similar difference between the two counties by gender.Although the intakes of selenium and iron per capita daily were actually little different between agricultural and pastoral counties, but the difference had statistical significance (p<0.05). By gender stratification, the intake of selenium of both male and female in the pastoral county were significantly higher than the corresponding population of agriculture county; the iron intake of female in pastoral county was significantly higher than agriculture area; the iron intake had no statistical difference between male in the two counties.Conclusions1、Build the detections of thyroid hormone in dried beef.2、The dried beef and milk contain thyroid hormone, thyroid hormone can be provide form meat and dairy for the use of body.3、Pastoral area residents the meat and dairy intake and the amount of thyroid hormone are significantly higher than agriculture area, it may be the one of the important reasons of the goiter prevalence difference between the two regions.4、The volume of selenium and iron of pastoral and agriculture area cannot meet the recommended intake. |
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