Continuous Lumbar External Drainage Of Clinical Preventive Chiari Malformation Type Ⅰ Study Of Postoperative Complications

Objective To investigate the clinical efficacy and safety of metformin combined with sitagliptin in type 2 diabetes patientsMethods:Choose Our hospital in January 2013-2014 May admitted malformation type I chiari 60 patients, 32 cases associated with syringomyelia. The enrolled patients were randomly divided into two groups, the treatment group and the control group of 30 patients 30. Treatment group in the first postoperative day trip lumbar catheter drainage, the control group in the first postoperative day lumbar catheter drainage is not the line, after a week of treatment, the use of their own before and after comparison between the experimental group and the comparison group and the control group the method, were observed simultaneously, regular biochemical tests of cerebrospinal fluid leukocyte results, changes in chloride content, glucose and protein content of quantitative indicators. Postoperative complications were observed after two groups of patients, such as fever, seroma, wound cerebrospinal fluid leakage, the incidence of intracranial infection, as well as wound healing and changes in length of stayResults1 Comparison of two synchronous cerebrospinal fluid biochemical indices.The results are shown in CSF biochemical examination: white blood cell count and protein quantification treatment group showed a downward trend, controls are decreased slowly, the two groups had statistically significant(P <0.05)2 Comparison of the two groups in the incidence of postoperative complicationsNone of the patients treated after intracranial infection control group, 5 patients with intracranial infection, the two groups p = 0.071, the difference was statistically significant. One patient treated postoperative subcutaneous fluid, the control group, 4 patients developed seroma, two groups p = 0.056, the difference was not statistically significant.3 Comparison of postoperative hospital stayTreatment group, the average number of days of hospitalization(10.564 + 2.236) days in the control group(14.354 + 1.532) days, the difference was statistically significant(P <0.01).4 Comparison of postoperative wound healingTreatment group and control group incisions healed well, no leakage of cerebrospinal fluid showed no difference in the two groups, no statistically significantConclusion:Chiari malformation type I routinely given after lumbar puncture and cerebrospinal fluid drainage catheters can effectively prevent postoperative intracranial infection, subcutaneous fluid, cerebrospinal fluid leakage and hydrocephalus occurs, can effectively reduce antibiotic use, shorter hospital stays in order to reduce the economic burden of patients with better clinical efficacy, worthy of promotion...