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Investigation Of High-sodium-diet In Patients With Hypertension In Western Hunan Ethnic Enclaves

Posted on:2016-07-21Degree:MasterType:Thesis
Country:ChinaCandidate:T T DengFull Text:PDF
GTID:2284330464962797Subject:Internal medicine
Abstract/Summary:PDF Full Text Request
Objectives : The purpose of this study was to analyze the hypertension patient data of Han and minority ethnic enclaves in Hunan west,to understand the causes of the prevalence of minority ethnic enclaves hypertension is higher than the Han population, and to explore ethnic enclaves crowd high sodium diet for electrolytes, cholesterol, high blood four blood pressure and other effects caused by the familiar high-sodium diet-induced pathogenesis of hypertension, for the treatment and prevention of hypertension in western Hunan minority provide solutions and new ideas.Methods: Collected standard western Hunan Han ethnic enclaves and hospitalized patients with hypertension, "the general hypertensive population in western Hunan questionnaire" and "western Hunan biochemical indices in patients with hypertension registration form" a total 612 copies, statistics minority and Han hypertension high sodium intake by the population proportion by χ2 test to compare minority and Han tables from prior education, high sodium habits, salt intake, family history and atrial natriuretic ferrite a(NPPA) genotypes was significant than other aspects. Comparative analysis using independent sample t test difference between minority groups and the Han group of high-sodium salt with the normal group with hypertension blood biochemistry, and take P = 0.05.Results: 1, patients with hypertension of minority in Western at culture constituent ratio, high salt habit proportions, daily sodium intake proportions and aspect ratio NPPA genotypes was statistically significant from Han hypertensive patients(P <0.05). Minority groups are relatively low education level, and has a high salt and other lifestyle habits, daily sodium intake higher than the Han group. 2, independent samples t-test results showed that:(1) minority group Na+(140.69 ± 3.35) higher than the Han group(138.19 ± 2.71)(P = 0.036). Minority groups triglycerides and LDL levels lower than the Han group(P <0.05); and a minority group angiotensin 4(1.24 ± 0.60) higher than the Han group(0.79 ± 0.57)(P ℃= 0.018).(2) minority group high blood sodium Na +(141.46 ± 3.28)Higher than normal sodium group(138.66 ± 3.45)(P = 0.043). And high-sodium group of high-density lipoprotein levels(1.26 ± 0.43) and angiotensin 4(1.55 ± 0.52) higher than the Han group(P <0.05).℃Conclusions: 1, the daily salt intake of patient in ethnic enclaves at western Hunan is higher than the Han minority, which can cause the level of blood Na +, angiotensin-A 4 ℃evaluate, thus affecting blood pressure. 2, NPPA mutant genotype is more in western Hunan minority population, the antihypertensive effect of diuretics may be better.
Keywords/Search Tags:ethnic enclaves, high sodium diet, hypertension
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