| Objective:In recent years, they are more compared single-vessel coronary artery disease with multi-vessel disease by age, Most of them research the risk factors of difference between the young and elderly, and young Group is less pure research. This study explores the risk factors of single and multi-vessel coronary artery disease in young patients with acute coronary syndromes. In order to investigate the relationship between the various risk factors and coronary artery lesions, interventions the risk factors of young patients with acute coronary syndrome and provides the reference for the judgment of illness. Methods:Selection of patients hospitalized for unstable angina and acute non-ST segment elevation myocardial infarction and ST-segment elevation acute myocardial infarction, which were first diagnosed by coronary angiography in first hospital of Jilin university Bethune cardiovascular disease diagnosis and treatment center during september 2013 to march 2015.A total of 312 patients with age 40 years old or less. They have medical records completely. Divided into two groups according to coronary.Angiography:Single coronary artery disease group:multi-branch arteries stenosis group:159 caces:153 caces., Divided into two groups according to gender:male 286 cases, female 26 cases. Unstable angina and acute non-ST segment elevation myocardial infarction were confirmed by Chinese guidelines (Chinese Medical Cardiology Subcommittee, Chinese Editorial Committee of Cardiology Journal,2012). Acute ST-segment elevation myocardial infarctions were confirmed by Chinese guidelines (Chinese Medical Cardiology Subcommittee, Chinese Editorial Committee of Cardiology Journal,2010). Decision criteria of coronary artery angiographic characteristics:coronary artery stenosis 50% or left main coronary artery stenosis is 40% is defined as a positive.Retrospective study was utilized. We recorded the Age, sex, smoking history, family history, history of high blood pressure, diabetes, blood pressure, blood lipid, fasting blood glucose, blood urea nitrogen, creatinine, and cardiac ultrasound results.Results:1. Compared with single coronary artery disease group and multi-branch arterie s stenosis group, it shows significant differences between hypertension and diabetes rate. The difference was statistically significant. Multi-branch arteries stenosis group had significantly higher hypertension and diabetes rate、Systolic blood pressure, dia stolic blood pressure, pulse pressure, total cholesterol, low-density lipoprotein in b1 ood, left ventricular end-diastolic diameter. Systolic blood pressure, diastolic blood pressure, pulse pressure, serum total cholesterol, LDL, left ventricular end-diastolic diameter increased with the branch.2. According to the results of regression analysis:gender, hypertension, diabetes, LDL, lipoprotein is an independent risk factor for coronary artery disease-count.3. Separate analysis of men with single coronary artery disease group and multi-branch arteries stenosis group, it shows significant differences between hypertension and diabetes rate (P<0.05).The difference was statistically significant. Multi-branch arteries stenosis group had significantly higher hypertension and diabetes rate, it shows significant differences between systolic blood pressure, diastolic blood pressure, pulse pressure, blood cholesterol, blood low-density lipoprotein, left ventricular end-diastolic diameter, lipoprotein (a).4. The left anterior descending artery is the most likely involved in young acute coronary syndrome with single-vessel disease.Conclusion:1. Compared with single coronary artery disease group and multi-branch arterie s stenosis group, it shows significant differences between hypertension and diabetes rate (P<0.05).The difference was statistically significant.Multi-branch arteries stenosi s group had significantly higher hypertension and diabetes rate. Compared with sin gle coronary artery disease group and multi-branch arteries stenosis group, it shows significant differences between Systolic blood pressure, diastolic blood pressure, pul se pressure, total cholesterol, low-density lipoprotein in blood, left ventricular end-diastolic diameter (P<0.05).Systolic blood pressure, diastolic blood pressure, pulse pressure, serum total cholesterol, LDL, left ventricular end-diastolic diameter increased with the branch.2. According to the results of regression analysis:gender, hypertension, diabetes, LDL, lipoprotein is an independent risk factor for coronary artery disease-count.3. Separate analysis of men with single coronary artery disease group and multi-branch arteries stenosis group, it shows significant differences between hypertension and diabetes rate、systolic blood pressure, diastolic blood pressure, pulse pressure, blood cholesterol, blood low-density lipoprotein, left ventricular end-diastolic diameter, lipoprotein (a). Multi-branch arteries stenosis group had significantly higher hypertension and diabetes rate.4. The left anterior descending artery is the most likely involved in young acute coronary syndrome with single-vessel disease. |
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