Research Protection Through The Yangshenyutangwan For Big Rat With Early Diabetes Mellitus On Renal Type Two

Purpose:High glucose and high fat diet mixing small amounts of food and primary STZ(Streptozotocin) two diabetes through the abdomen using large inflatable rat, biological chemistry and immunological analysis utilizing harmonized method type figure Yangshenyutangwan two diabetes rat for glucose and insulin in large horizontal effects of kidney function, discuss and study of type two diabetes involved in the action of a big rat kidney for the Yangshenyutangwan.Methods:Researchers selected ninty healthy male SD large rats and divided them control group and model control group. Blank control group of fifteen of them are free and usually feed water to drink. The rest of control group is continuously fed high glucose and high fat diet food four weeks. After 1% STZ was injected into the 30mg/kg in the primary stomach. The blood glucose 16.7mmol/L or more of type two diabetes rat model was a big success. Forward models opposition groups, the low-dose group of the Yangshenyutangwan, high-dose group of the Yangshenyutangwan, Metformin hydrochloride group (vow control group), Diabetic group (traditional Chinese medicine control group) were randomly separated into five groups total. In the corresponding drug it was measured and the primary blood glucose every fifteen days; After you put the two months related changes in serum insulin level(FINS) and renal fuction(BUN, Ua, SCr, TRF, mALB), in the kidney CD 34+, the PAI-1 content was measured by immune harmonizedlaw, through the MAS staining form crystals observed for kidney tissue.Results:1. Compounding the high glucose and high fat diet food Gaudens STZ to the abdomen and a small amount of primary infusion made a big rat of type two diabetes, Yangshenyutangwan has made it possible to improve the general health of the larger rat of type two diabetes due to STZ.2 Effect on blood glueose:After two months of irrigation, Blood glucose in SD rats on high group of the Yangshenyutang had a large drop, anther control did not show any differences relatively.3. Effect on insulin level:Compared with model group Yangshenyutangwan has made it possible to lower the clear insulin levels.4. Effect of the indication of the renal function:as compared to other control group, Yangshenyutangwan a group of type two diabetic rat in large BUN, Ua, SCr, TRF, mALB level was lowered all clear.5. Effects on Pal-1 and CD34+:As copared to other control group, Yangshenyutangwan in the high dose group of type two diabetic rat Cd34+large and Pal-1 level was clearly lowered.Conclusion:Yangshenyutangwan is to lower your blood glues and insulin level, while lowering the urine transferring and urine protein in urine, thereby reducing the effect of renal function indicators. Such a system improve the blood glues level, and enabling an improvement through the blood vessels in the renal function, and the second type operation of the protection of the kidney in diabetes rat...