A Meta Analysis Of Clinical Efficacy Of Tubular Stomach Compared With Whole Stomach For Reconstruction In The Resection Of Esophageal Carcinoma

Objective:To evaluate the clinical efficacy of tubular stomach compared with whole stomach for reconstruction in the resection of esophageal carcinoma. Method s:The RCTs were searched from Pubmed、OVID、CNKI、Wangfang、Super star d-igital library、CMB and Baidu、Google search engine on central venous catheter c-losed drainage of pleural cavity combined with negative pressure suction in the tre-atment of spontaneous pneumothorax.Two searchers selected studies based on the i ncluded criteria strictly, Used the criteria of Cochrane Collaboration to appraise the quality of RCTs used GRADEprofiler3.6.1 software for quality evolution and used Revman5.3 for data analysis and management. Results:The 12 RCTs including 41 37 patients were enrolled. The tubular stomach group compared with the whole sto-mach group, the incidences of anastomotic leakage[OR=0.72,95%CI(0.54,0.96)]、t-he incidences of reflux esophagitis[OR=0.22,95%CI(0.12,0.41)]、the incidences of thoracic stomach syndrone[OR=0.16,95%CI(0.11,0.23)], the tubular stomach group wasless than the whole stomach group, the incidences of anastomotic stenosis[OR= 0.74,95%CI(0.33,1.69)]there were no significant difference. Conclusion:The treat-ment oftubular stomach for reconstruction in the resection of esophageal carcinoma is a safe and effective operation. However, the RCTs included are only English st-udies and Chinese studies, there is publication bias and some sample size is small, the large sample of high quality clinical trials of RCT are still needed for further confirmation.