The Study Of Relationships Between Cervical Lesions And Slenium Of Countryside Uyghur Women From Bachu County Of Kashi Region Of Xinjiang

Objective:Through the study on the content of serum selenium of Uygur women with cervical lesions of rural areas of Xinjiang Kashi Bachu County, In order to investigate the relation between selenium and cervical lesions, Provide nutritional basis for the intervention of cervical cancer.Methods:① According to Bachu county geographical location,population distribution,economic status,randomly selected six townships plus three town of married women 20-65 years 5,045 people for the survey,the use of interviews conducted a questionaire survey of women’s basic information,gynecological examination,TCT detection,care HPV detection and VIA/VILI detection from March 1,2014 to June 15,2014.The care HPV positive、TCT results for ASCUS or more lesions use cervical biopsy under colposcope, Using the data of EpiData database two times the input arrangement.②The selenium content in serum were detected in 115 cases of pathological results was CIN I above (including CIN I) and 173 patients of cervical chronic inflammation by graphite furnace atomic absorption spectrometry.③All data were put into computer and were analyzed by using SPSS 17 package,Groups were compared using Spearman test analysis selenium content,The remarkable test level was provided P<0.05 in double sides.Results:①The serum content rank mean of selenium in cervical lesion group and control were 97.32 and 175.86 respectively; The median value of serum content of selenium in cervical lesion and control were 0.019 and 0.026 respectively.The serum content of cervical lesion lesion group significantly lower than the control,and showed statistically significant(P< 0.05).②HPV positive patients with HPV negative comparison:The serum content rank mean of selenium in cervical lesion group of HPV positive and HPV negative were 58.71 and 54.17 respectively; The serum content rank mean of selenium in control group of HPV positive and HPV negative were 88.57 and 85.23 respectively; The serum content of cervical lesion lesion group and control of HPV negative Slightly lower than the HPV positive,and showed no statistically significant(P>0.05).③The serum content rank mean of selenium in cervical lesion group of HPV positive and control of HPV positive were 70.05 and 120.57 respectively; The serum content rank mean of selenium in cervical lesion group of HPV negative and control of HPV negative were 25.61 and 55.96 respectively; No matter in HPV positive or HPV negative group,The serum content of cervical lesion lesion group significantly lower than the control,and showed statistically significant(P<0.05).Conclusions:Cervical lesions in Uygur women in rural areas of Xinjiang Kashi Bachu county may have a certain relationship with selenium deficiency,The relationship between HPV infection and patients with selenium remains to be further studied.