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Type 2 Diabetes Retinopathy Blood Parameters Analysis

Posted on:2016-01-20Degree:MasterType:Thesis
Country:ChinaCandidate:B H YangFull Text:PDF
GTID:2284330464955164Subject:Ophthalmology
Abstract/Summary:PDF Full Text Request
Objective:the objective of this study is to formulate the correlation between glycosylated hemoglobin (HbAlC), C-reactive protein (CRP), blood lipid; D-dimer (D-D) and serum bilirubin in diabetes mellitus type 2 patients and hence evaluating the relationship between diabetic retinopathy (DR) and the latter.Methods:A sample of 258 patients with eye disease in 129 cases of patients with type 2 diabetes group were surveyed and the presence of diabetic retinopathy and degree of pathological changes were analyzed among them and furthermore divided into three groups:NR, NPR and PR correlating them with HbAlC, CRP, blood lpid (TC, TG, HDL, LDL-C-C), D-D and serum bilirubin (TBIL, DBIL, IBIL) content detection and statistical analysis.Results:HbAlc concentration NR group, NPR group and PR group, CRP levels, serum DD value, TQ TBIL, IBIL and TC levels were statistically significant (P<0.05). But no significance difference (P> 0.05) was noted in HDL and LDL while multivariate unconditional Logistic regression analysis showed that DD had no significant difference in the correlation with the DR IBIL (P> 0.05). HbAlC, CRP and age of DR independent are the common risk factors and the last but not the least TBIL is a protective factor DR.Conclusion:HbA1C is a risk factor for DR; CRP is an independent risk factor for the severity of DR, TG DR severity with increasing trend of aggravation. While regulating body dyslipidemia can effectively delay the progression of DR. Hence DD, diabetic retinopathy and the development of relevant TBIL protective factors can improve the body’s state based on blood-related indicators and can also reduce the incidence of DR.
Keywords/Search Tags:diabetic retinopathy, blood parameters, correlation
PDF Full Text Request
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