The Study Of Correlation Of MRI-DWI, ~1H-MRS And LDL-C In NAFLD

Objective: In order to improve the accuracy of clinical diagnosis in nonalcoholic fatty liver disease, we analyzed the correlation of MRS, DWI, and the low density lipoprotein serum concentration in nonalcoholic fatty liver disease.Methods: The control group include 39 subjects of healthy physical examination in the hospital, the observational group include 39 patients of nonalcoholic fatty liver disease. Two groups of subjects were examined with magnetic resonance imaging-diffusion weighted imaging, magnetic resonance spectroscopy and low density lipoprotein cholesterol assay, compared two groups of test results, analysis the correlation of DWI, MRS, and LDL-C.Results: The results of MRS have significant difference between two groups, P<0.05; magnetic resonance spectroscopy in the areas under the peaks, lipid water ratio and low density lipoprotein cholesterol levels have positive correlation, the ADC value of b at 1000s/mm2 was negatively correlated with low density lipoprotein cholesterol, P<0.05.Conclusion: MRS and DWI were closely related with LDL-C in nonalcoholic fatty liver disease. MRS and DWI could semiquantitatively analyze the fat metabolism of liver, and provide more information for clinical diagnosis of nonalcoholic fatty liver disease.