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The Study Of Buzhongyiqi Method In The Treatment Of Hemorrhoids Prolapse Of Serology Matrix Metalloproteinases 9

Posted on:2016-02-02Degree:MasterType:Thesis
Country:ChinaCandidate:Q J WangFull Text:PDF
GTID:2284330461981893Subject:Traditional Chinese medicine
Abstract/Summary:PDF Full Text Request
ObjectiveHemorrhoids sickness development diffirent theory and the theory guide treatment, understanding of hemorrhoids sickness enough clear, comprehensive, treatment of hemorrhoids sickness, there is no absolute safety, fewer complications, and symptoms of method. In domestic at present based on the study of mixed hemorrhoid, through further research, clinical data collection methods, looking for serologic test project to dynamically observe the degree of danger of the development of the mixed hemorrhoids prolapse, understanding the onset of the resulting process. Hemorrhoids sickness development in protein levels clear explanation. Also shows that the mixed hemorrhoids prolapse degeneration have close correlation with aging. The aim of this topic, namely support fibulin proteins on Ⅱ correlation, Ⅲ hemorrhoids prolapse of development. In the process of treatment of patients with intense discomfort, hope to be able to process and increase the treatment before and after treatment, reduce or eliminate the patient’s discomfort.MethodsThis study based on clinical patients with four diagnosis and physical examination, diagnosis, dialectical to separate different type, using the corresponding treatment, undergoing elective surgery. In elective surgery process before and after the acquisition of different syndrome types of mixed hemorrhoid or hemorrhoids patients serum, adsorbent by enzyme-linked response measurement, observation result determination of MMP-9 levels in serum in patients with preoperative and postoperative changes, and symptoms of quantitative score changes of the patients before and after treatment. Statistical treatment:use spss18 package, t test, p<0.05 for the difference is statistically significant.ResultsChange the content of each MMP-9 results shows:spleen deficiency type of mixed hemorrhoid patients after surgery and treatment process, oral drug or surgical intervention in patients with the level of MMP-9 before treatment were decreased; Oral supplement yiqi granules group than those in the oral drugs or oral sweet clover flow immersion group of low level of MMP-9. Oral supplement in yiqi granules and sweet clover flow of immersion group level than oral sweet clover flow immersion group of low level.ConelusionOral supplement in yiqi granules, sweet clover extract can inhibit Ⅱ, mixed hemorrhoid Ⅲ degrees or hemorrhoids patients serum level of MMP-9. Yiqi granules group and oral of lower degree less oral drugs or not taking to fill in the low level of patients with yiqi granules. Oral drugs and surgery to alleviate the anal cushion structure of local microcirculation, improve anal cushion ischemia oxygen deficit, deferred the microenvironment of hemorrhoids sickness occurs, then influence fibulin proteins function promote hemorrhoid process of structure damage, namely the MMP-9 the degradation process of cylinder pad support structure.
Keywords/Search Tags:buzhongyiqi, Matrix metalloproteinases 9, hemorrhoids, prolapse pixu (spleen deficient)
PDF Full Text Request
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