The Clinical Research Of Wen Tong Branch In The Treatment Of Sepsis Yang Relieving Empirical Gastrointestinal Dysfunction

Objective:This research mainly to observe flawored rhubarb monkshood soup treatment the clinical effect of sepsis patients with FGID, discusses wen tong play to improve sepsis in Yang deficiency of relieving the empirical significance of gastrointestinal dysfunction mechanism and effects on inflammatory factors.Methods:This topic selection 60 patients with sepsis treatment in shenzhen hospital from September 2012-September 2014, based on the principle of stochastic, alone-blind,60 Cottoms of subjects were randomly separat into the two organizes, treatment group 30 cases besides western medicine comprehensive treatment, combined with flawored rhubarb monkshood soup decoction,200 ml, in the morning and warm clothing or nasal feeding 100 ml, a dose, the control group 30 cases in addition to the western medicine comprehensive treatment, and with moser shall be 15 mg+200 ml warm water, early, middle and late three times warm clothing or nasal feeding;Treatment for 7 days. Observation comparison before and after 7 days treatment of TCM in pepole with sepsis symptoms integral, gastrointestinal function score and APACHE II rating score changes, and PCT, WBC and CRP change.Results:Curative effect:7 days after treatment, flawored rhubarb monkshood soup is moser will benefit groups of TCM symptoms reduced total integral, contrast between the two groups have significant difference (P<0.05);7 days after treatment, two groups of their respective scores were lower gastrointestinal function, flawored rhubarb monkshood soup flavored group drop degree is more obvious than moser will benefit group, with statistical significance (P<0.05);Two groups of APACHE Ⅱ reduced score 7 days after treatment, compared with moser will benefit groups, flawored rhubarb monkshood soup flavored group drop is more obvious, with statistical significance (P<0.05).7 days after treatment, flawored rhubarb monkshood soup flavored group total effective rate was 87%, moser will benefit group total effective rate was 60%, two groups are statistically significant (P<0.05);Treatment group 28 days mortality was 6.7%, the control group 28 days mortality was 10.0%, comparing differences between two groups have statistical significance (P<0.05).Inflammation index:a week after the flawored rhubarb monkshood soup treatment group, two groups of cases compared with pre-intervention PCT values have been falling, the WBC count, CRP values, compared with moser will benefit groups, flawored rhubarb monkshood soup flavored group of land value of PCT and CRP value degree is more obvious, statistically significant difference (P<0.05);But the WBC count between the two groups after treatment, no significant (P>0.05).Safety indicators:respectively before and after treatment in both groups, and the two groups after treatment of liver function (ALT, AST), kidney (BUN, Cr) check index had no significant difference.Conclusion:The results confirmed that based on principles of wen tong branch in fitting into a flawored rhubarb monkshood soup can significantly improve sepsis patients with gastrointestinal dysfunction Yang deficiency relieving empirical state of clinical symptoms, gastrointestinal function, improve the invalid’s inflammatory activity, improve the patient’s condition severity, improve the treatment efficiency, reduce the 28-day death rate, ameliorate the consequence of patients, for the application of TCM can improve the effect of the cure of sepsis is have high clinical application value to guidance for clinical Syndrome differentiation and treatment of sepsis gastrointestinal dysfunction provides a new choice.