Study On Toxicological And Hygiene Assessment Of A Health Care Products Of Animal And Plant Mixture

In recent year, due to the deterioration of the environment, food safety increasingly insecure, the growing pressure of life and other reasons, leading to the rising incidence of chloasma. At the same time, more and more people began to pursuit good quality of life the health care product consumer demand is increasingly growth. Gansu Provence because of the unique geography, weather conditions and a wealth of animal and plant resources which have are a large positive effect of human health. In order to effectively utilize the advantage of the natural resources in Gansu Provence, we combine market demand use the Chinese medicine theory Create a health care product with good effect of rid melasma and regulate bodily functions.The results showed that:1. Health care products for female and male mice acute oral toxicity, maximum tolerated dose (MTD) were greater than 20g/kg BW.2. Three genotoxicity tests (Ames test, mouse bone marrow cell micronucleus test and sperm abnormality test) results were seen in the health care products have no mutagenic effect.3. In 1.5,3.0,6.0g/kg WB dose gavage to rats health care products for 30 days, the rats activity, growth and development, body weight, food utilization, hematology, blood biochemistry, dirty body ratio and disease physical examination results were not reflected in its adverse effects.4. Indicators of the hygiene and health products are in line with national standards, nutritious ingredients.5. Accelerated stability test found that under the experimental conditions, the content of saponins, a functional components of the product, there was greater variation, reduced to 0.10g/100g.