Risk Factors For 894 Cases Of Esophageal Cancer Patients With Preoperative Nutritional Risk And Analysis Of The Relationship Between Nutritional Status With Prognosis

Objective:To provide the reference basis for reducing the occurrence of nutritional risk by analyzing possible risk factors for nutritional risk status and investigating the relationship between preoperative nutritional risk status and prognosis.Methods We retrospectively analyzed the clinical data of 894 patients (nutritional risk group of 491 cases, non-nutritional risk group of 403 cases) with esophageal cancer resection. The univariate analysis was used to analyze the relationships between nutritional risk status with postoperative complications and length of hospitalization. And the multiple Logistic regression model analysis was applied to analyze the risk factors of nutritional risk status.Results The nutritional risk group had a higher rate of postoperative complications (33.61%vs19.60%, u=-3.429, P=0.001),higher incidence of serious complications (23.01%vs8.68%, u=-3.611,P=0.000) and longer hospital stays (37.20±13.89vs31.69±13.49, t=4.124,P=0.000) than that of non-nutritional risk group. The results of the multiple Logistic regression analysis showed that the preoperative nutritional risk factors were associated with the patients’ age (OR=1.58,95%C1=1.101-2.268) number of symptoms entries (OR=7.97,95%C1=6.071-10.463), symptom severity (OR=0.26,95%C1=0.186-0.385), and dietary intake (OR=0.62,95%C1=0.482-0.813) (P< 0.05 for all).Conclusion The older patients with more severe symptoms and poor diet are more likely to suffer from nutritional risk. Prolonged hospital stay and postoperative complications easily happen in patients with nutritional risk. So patients with preoperative nutritional risk should be given timely and effective nutrition intervention measures, in order to reduce postoperative complications and length of hospitalization.