Relationship Between The Plasma NPY And Hs-CRP And LVEF In Chronic Heart Failure Patients With Ejection Fraction

Objective:1. To investigate the changes of plasma concentration of Neuropeptide Y and hs-CRP in Chronic Heart Failure Patients with ejection fraction.2. To study the relevance of the plasma neuropeptide Y, hs-CRP and the Left ventricular ejection fractions in heart failure patients with left ventricular ejection fraction.Method:1. Fifth heart failure patients with left ventricular ejection are selected into the experimental group. In the next morning fasting venous blood was collected at elbow which were used to measure the plasma neuropeptide Y and hs-CRP. On the same day we would measure their LVEF with heart color ultrasound. In 7 days after treatment the same indexes would be measured again.2. The other physical normal fifth people are selected as healthy controls.Result:1.Compared with the control group, the neuropeptide Y and hs-CRP of the experimental group before the treatment(P<0.05),and the lower LVEF, the higher plasma concentration of the two indexes.2.The neuropeptide Y and hs-CRP levels of the Experimental group decreased significantly after treatment(P<0.05).3.The LVEF in the experimental group compared with control group decreased significantly(P<0.05).4.The plasma neuropeptide Y and hs-CRP level are negatively correlation with the LVEF in these patients.Conclusion:1. According to our study, Neuropeptide Y and hs-CRP may involve in the decrease of ejection fraction in heart failure people, and the higher concentration, the worse of heart function.2. Neuropeptide Y and hs-CRP have certain relevance with the left ventricular ejection fraction, with the increase of the two levels, ventricular blood weakened.3. Combined neuropeptide Y with hs-CRP can improve the accuracy of evaluating cardiac function in patients with heart failure.