| Objective: research nano bone implant combined with percutaneous minimally invasive fixation treatment thoracolumbar osteoporotic fractures of the clinical curative effect, and compared with percutaneous vetebroplasty in the treatment of thoracolumbar osteoporotic fracture.Methods: selection in March 2012 to June 2014, 48 cases of thoracolumbar osteoporotic fractures, were randomly divided into group A and B, which is suitable for experimental group A, A total of 20 cases of group B as control group, A total of 28 cases, group A for nano bone implant treatment combined with percutaneous minimally invasive fixation, group B treatment for the injury of the vertebral pedicle of vertebral body bone cement injection, collected from patients with preoperative and postoperative, postoperative follow-up(for postoperative follow-up time in March, June, December) clinical data, including the injured vertebra leading edge height, Cobb Angle, review preoperative MRI contrast after understanding of adjacent segment disc degeneration situation change, the patient pain. By Sp SS13.0 statistical software to establish a database statistics, analysis of the method of injured vertebral height change, Cobb Angle changes, the degree of pain for paired or not paired t test, analysis of variance(P< 0.05, differences have significant meaning). Clinical effect evaluation with Kruskal Wallis test.Results: 1. the experimental group all cases of postoperative changes compared with the preoperative fanterior flange height, and preoperative fanterior flange height data statistics, there are significant differences(P < 0.05).2.the experimental group, all cases of postoperative compared with preoperative Cobb Angle have markedly improved, and the Cobb Angle data statistics, there are significant differences(P < 0.05).3.postoperative review of magnetic resonance imaging(MRI) in December, the experimental group and control group in the differences of adjacent segment disc degeneration has no statistical significance(P > 0.05).4.experimental group all cases of preoperative VAS score and postoperative 1 week, march, June, December VAS score obtained obvious changes, the data statistics has obvious difference(P < 0.05).5.group of 20 patients with postoperative follow-up of 1 year to all of the patients were performed MRI and 8 case oe intervertebral discobvious degeneration, and the rest 12 cases of adjacent segment disc without a significant increase.6.control group in all cases of preoperative VAS score and postoperative 1 week, march, June, December VAS score improved significantly, postoperative and preoperative data statistics, there are significant differences(P < 0.05).7.the control group, 28 cases of postoperative follow-up of 1 year to all cases were performed MRI, compared with the preoperative MRI examination, 12 cases of injured vertebral stage of adjacent intervertebral disc degeneration significantly worse condition.8.after 1 week, march, June, December review imaging data shows in injured vertebral leading edge height change between the two groups, Cobb Angle changes more significant difference(P < 0.05).9.after preoperative and postoperative 1 week and 3 months postoperatively in June, there was no difference in two groups of VAS score 12 month(P > 0.05).Conclusion: nano bone implant combined with percutaneous minimally invasive fixation and the injured vertebral pedicle of vertebral body bone cement placement, also has the advantages of small trauma, rapid recovery, and its in restore vertebral body height, improve the Cobb Angle, avoid the loss of vertebral body height and the Cobb Angle has an obvious advantage is an effective way of treating thoracolumbar osteoporotic fracture.Can slow down the adjacent segment disc samples need more cases and longer follow-up times. |
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