Clinical Study Of Qi Deficiency Blood Stasis Type Acute Cerebral Infarction Heart Syndrome Clinical Features And Naoluoxintong Intervention

Objective Observation of qi deficiency blood stasis type and clinical features of acute cerebral infarction complicated with brain heart syndrome and TCM Naoluoxintong intervention of clinical efficacy and safety.Method Selected patients belongs to qi deficiency blood stasis with acute cerebral infarction complicated with brain heart syndrome and can complete the task of 60 patients with clinical trials, using randomized controlled methods, randomly divided into two groups,the treatment group and control group 30 cases each. The control group were given conventional anti platelet aggregation, improvecirculation, scavenging free radicals,anticoagulation, maintaining water and electrolyte balance of symptomatic and supportive treatmeat. Treatment group on the basis of control group therapy for Naoluoxintong oral. Two groups of a course of 21 days. Changes were observed before and after treatment of two groups of TCM symptoms, Observe the two groups before treatment and after treatment for 7 days, 14 days, 21 days of electrocardiogram, heart type fatty acid-binding protein, ischemia modified albumin, allergic protein C reflect,troponin, brain natriuretic peptide,Glasgow coma scale, neural function defect scale changes, and compared between groups.Results1) Patients with Qi deficiency blood stasis type with acute cerebral infarction complicated with brain heart syndrome clinical features: Except cerebral infarction,aphasia, hemiplegia and sensory disorder symptoms, at the same time there is flustered,chest tightness, shortness of breath, even cardiac insufficiency, angina pectoris,sweating, dim t Arrhythmia of 46 patients with 60 cases, the abnormal rate was 76.7%,mainly for various period before contraction, abnormal waveform for 32 cases,abnormal rate was 53.3%; Basal ganglia infarction 40%, thalamus infarction 31.7%,cerebellar infarction 28.3%, basal ganglia cerebral infarction complicated with brain heart syndrome.2) Two groups of TCM symptoms after treatment than before treatment were improved,TCM syndrome integral comparison between the two groups, 7 days after treatment,two groups of symptom scores through the comparison of traditional Chinese medicine has no obvious difference(P > 0.05), days 14 and 21 days in the two groups after treatment of TCM syndrome integral are reduced, there were significant differences(P> 0.05).3)The two groups after treatment ecg was improved, comparison between the two way,3 days, 7 days, 14 days after treatment in the two groups electrocardiogram(ecg)changes by the statistical test has no obvious difference(P > 0.05); 21 days after treatment in treatment group electrocardiogram improved significantly, there were significant differences(P > 0.05).4)The two groups after treatment serum heart type fatty acid binding protein level was decreased, the comparison between the two groups, 7 days after treatment, 14 heavenly heart type fatty acid binding protein decreased, but no significant difference(P > 0.05);21 days after treatment in treatment group heart type fatty acid binding protein significantly lower than the control group, with significant difference(P > 0.05).5)Two groups after treatment serum ischemia modified protein level was decreased, the comparison between the two groups, the treatment for 7 days, 14 days, 21 days after ischemia modified protein level of treatment group was obviously lower than the control group, with significant difference(P < 0.05).6)Glasgow coma scale the two groups after treatment was obviously improved, and the comparison between the two groups, two groups of 7 days, 14 days after treatment has no obvious difference(P < 0.05); 21 days after the treatment the treatment group is significantly higher than the control group, with significant difference(P < 0.05).7)Neural function defect scale the two groups after treatment than before treatment, the comparison between the two groups, two groups of 7 days, 14 days after treatment there was no significant difference(P < 0.05); 21 days after treatment significantly lower than the control group, treatment group had significant difference(P < 0.05); 7 days of treatment group after treatment, 14 days, 21 days of neural function defect scale efficiency are 46.66%, 63.33% and 46.66% respectively; Efficient and control group were 36.66%, 56.66%, 80.00%, two groups of 7 days, 14 days after treatment has no obvious difference(P > 0.05); 21 days of the two groups after treatment, treatment group was obviously lower than the control group, with significant difference(P <0.05).8)The two groups after treatment serum hypersensitive c-reactive protein was decreased,the comparison between the two groups, 7 days, 14 days after treatment, 21 days of treatment group serum hypersensitive c-reactive protein level significantly lower than the control group, with significant difference(P < 0.05).9) Two groups after treatment serum troponin level was decreased, the comparison between the two groups, 7 days, 14 days after treatment, serum troponin levels 21 days of treatment group was obviously lower than the control group, with significant difference(P < 0.05).10)The two groups after treatment serum brain natriuretic peptide level was decreased,the comparison between the two groups, 7 days, 14 days after treatment, brain natriuretic peptide levels 21 days of treatment group was obviously lower than the control group, with significant difference(P < 0.05).11)Changes in the groups after treatment in patients with cardiac ultrasound treatment before no obvious improvement.Between the two groups before treatment echocardiographic left ventricular ejection fraction analysis, there was no significant difference(P>0.05); 21 days after treatment between groups is still no significant difference(P < 0.05).Conclusion1 Patients with acute cerebral infarction complicated with brain heart syndrome clinical characteristics of diversification, the brain xin tong can effectively improve the anomaly indicators.2 The Naoluoxintong can reduce the patients with acute cerebral infarction complicated with brain heart syndrome of traditional Chinese medicine symptom integral.3 The Naoluoxintong can significantly improve patients with acute cerebral infarction complicated with brain heart syndrome ecg waveform.4 The Naoluoxintong can obviously reduce the patients with acute cerebral infarction complicated with brain heart syndrome heart type fatty acid binding protein levels.5 The Naoluoxintong can obviously reduce the patients with acute cerebral infarction complicated with brain heart syndrome ischemia modified protein levels.6 The Naoluoxintong can obviously increase the patients with acute cerebral infarction complicated with brain heart syndrome Glasgow coma scale, can significantly improve the patients’ consciousness.7 The Naoluoxintong can obviously reduce the patients with acute cerebral infarction complicated with brain heart syndrome neural function defect scale, can obviously improve patients with nerve function.8 The Naoluoxintong can obviously reduce the patients with acute cerebral infarction complicated with brain heart syndrome serum hypersensitive c-reactive protein level.9 The Naoluoxintong can obviously reduce the patients with acute cerebral infarction complicated with brain heart syndrome troponin protein levels.10 The Naoluoxintong can obviously reduce the patients with acute cerebral infarction complicated with brain heart syndrome serum brain natriuretic peptide levels.11 The Naoluoxintong of echocardiographic left ventricular ejection fraction improvement is not obvious.