| Objective:To study the factors related in the prognosis of patients with colorectal cancer and diagnosed with having mesenteric tumor nodules, in order to plan out proper clinical treatment, and to improve the survival time and the quality of life of patients diagnosed with colorectal cancer and having mesenteric tumor nodules.Method:Using retrospective analysis as researchmethod, taking as object of study patients from the First Affiliated Hospital Of Guangxi Medical University Colorectal and Anal Surgery Department_from 1st January 2011 to 31stDecember 2013 having already undergone surgical treatment and whose pathology results clearly confirm the diagnosis of colorectal cancer accompanied by mesenteric tumor nodules.Patients’information (was collected) such as gender, age,tumor location, tumor size,tumor pathology type, tumor differentiation degree, tumor classification, Tand N stage, number of tumor nodules/cancerous nodule, CEA, CA199 results, neural invasion and vascular invasion.According to the inclusion standard, eligible patients were followed up for, the start time of the follow-up was when the pathological results came back, the cut-off time was 31st December,2014, and the end point time was until death or loss to follow-up.Using SPSS 16.0 statistical software for data analysis, using COX regression model to analyze the various factors, the independent factor affecting survival_of patients diagnosed with colorectal cancer and having mesenteric tumor nodules was obtained.P<0.05 was statistically significant.Results:Of the 63 cases of colorectal cancer patients with mesenteric tumor nodules, there were 38_males_and 25 females; Age group was between 17 to 80 years of age with the youngest one 17 years old and the oldest one at 80 years old;Location of tumor:there were 30 cases of tumor found in the colon and 33 cases where the tumor was found in the rectum;Size:27 cases were less than 5cm_and 36 cases where the size was greater or equal to 5cm;Types of tumors:there were 37_ulcerative cases,15_infiltrative cases and 11 mass-type cases; Pathology type:there were 49 cases of adenocarcinoma,12 cases of mucinous carcinoma and 2 othercases;The degree of differentiation:the tumor cells were well differentiated in 3 cases, moderately_differentiated in 37 cases and poorly differentiated in 23 cases;T stage classification:there was one case of T2,56 cases with T3 and 6 cases of T4;N stage classification:there were 23 cases of NO,19 cases of N1 and 23 cases of N2;Vascular invasions:there were 17 cases with vascular invasions and the other 46 cases had no vascular invasion; neural invasion:only 7 cases of neural invasion werewhile there was no neural invasion in the other 56 cases; Preoperative CEA:an increase/rise in the preoperative CEA values were observed in 34 cases, while being normal in the other 29 cases;Preoperative CA199 values:an increase/rise in the preoperative CA199 values was observed in 20 cases, and normal values were recorded in the other43 cases;Cancer nodule number:there were 43 cases in which the number of cancer nodules recorded was less than 3, and there were 20 cases in which the number of cancer nodules was greaterthan or equal to 3.Conclusion:1.Age, tumor sizes, TNM staging, number of mesenteric nodules, histological grading are independent factors that affecting the survival of the CRC patients with mesenteric nodules.2. Average lifespan of patient with tumor size equal or more than 3 is shorter than the one with smaller than 3.3. The average survival time of mesenteric cancer nodules patient without lymphatic spread are longer than the patient with lymphatic spread.Lymph node number less than 4 have the longer mean survival time than the lymph node number greater than or equal to 4. |
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