Study Of Death-related Factors Of Patients With Acute Exacerbation Of Chronic Obstructive Pulmonary Disease

Objective:To determine the high risk of in-hospital patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD).Methods:Retrospectively analyzed 4624 cases of hospitalized patients with chronic obstructive pulmonary disease(COPD) from January 2005 to December 2014 in the Second Hospital of Hebei Medical University. According to the patient’s survival state, divided into death and survival group. Apply Epidata 3.1 to establish the database, using double entry check and spss19.0 for statistical analysis with the inspection level alpha was 0.05. t test, the chi-square test(test) and Logistic regressions were used for or single factor and multiple factors analysis.Results:Death-related factors include: PCO2, complications, mecha nical ventilation, support treatment, lung function grade, PO2, pulmonary infection, acute episodes, length of the course of the disease, BMI, the age, and so on. The main complications were Pneumonia(68.2%), cor onary heart disease(49.7%), pulmonary heart disease(47.8%), heart failur e(38.2%) and hypertension(36.9%), arrhythmia(26.8%), diabetes(15.9%) and bronchial asthma(12.1%), acute myocardial infarction(10.2%), gastrointestinal bleeding(10.2%), lung cancer(9.6%),renal-insufficiency(7.0%)pulmonary fibrosis(8.3%),bronchiectasis(5.7).Conclusion:Chronic obstructive pulmonary disease is a development disease, affected by the interaction of many factors, risk factors dangerous extent of elevated PCO2, complications, mechanical ventilation, support treatment, pulmonary function grade, acute episodes, time, age, duration of; Complications in addition to the respiratory system disease, other system diseases and cause the high risk of death in patients with COPD, therefore with general system and organ protection is very important for the prognosis of patients with COPD.