To Investigate The Effects Of Different Treatment Options For Patients With Acute Coronary Syndrome

Objective Investigate the impact of different treatment strategies in the acute coronarysyndrome (ACS) patients with percutaneous coronary intervention (PCI) perioperative periodon short-term (30d) and long-term (one year) outcomes.Methods Collecting200patients of ACS and have underwent PCI from NingxiaMedical University General Hospital Cardiovascular Department between September2011and September2012, All of the patients signed consent form. Collate summary all thepatients’ treatment strategies after PCI. Follow-up the records of all patients from30days to1year of different treatment options, and follow-up records of patients30days to1year ofthe occurrence of major adverse cardiac or cerebral event(MACCE) and cases of death.(1) Analysis after PCI treatment strategy:We summarized the perioperative drug therapy,according whether using low molecular weight heparin, Beta blockers, angiotensinconverting enzyme inhibitors, statins, calcium channel blockers and drug-eluting stentsdivided them into two groups respectively. And used a chi-square test and t-test analysis alldatas. Exploreing the relationship between the use of drugs after PCI and age,gender,,historyof present illness, past history (myocardial infarction, diabetes, hypertension, highcholesterol), heart failure.(2) The result analysis of following-up30days: According whether using tripleantiplatelet agents, low molecular weight heparin, Beta blockers, angiotensin convertingenzyme inhibitors, statins, calcium channel blockers and drug-eluting stents divided theminto two groups respectively. Exploreing the relationship between different treatment regimens in patients with MACCE after30days in the ACS patients.(3) The result analysis of following-up1year: Continue to use the above groups,exploreing the relationship between the ACS patients with different treatment regimens andMACCE and the deaths occurrence after1year.Results(1) Analysis after PCI treatment strategy By analysis perioperative therapy on200cases.According we can see that the baseline (age, gender, past history) in groups by heparin,calcium channel blockers was similar (P＞0.05). while there were nuances of previousmedical history in groups of statins, ACEI,Beta blockers, and DES. Depending on whetherstatins, β-blocker group, ACEI and DES there are some significant differences (P <0.05),respectively in high blood pressure, age, heart function, and diabetes.(2) The result analysis of following-up30days:The incidence of MACCE in one month isrelated with Whether using drugs of statins, Beta blockers, ACEI, triple antiplatelettherapy(Aspirin, clopidogrel, Tirofiban) and DES (P<0.05)(3) The result analysis of following-up1year: The use of Beta blockers, ACEI, statins,DES reduce mortality in patients1year. DES and triple antiplatelet therapy also takeeffective roles in reduce the incidence of MACCE..Conclusion(1)In accordance with the guidelines application statin, beta blockers, ACEI, may reducethe incidence of MACCE within one month in ACS patients.(2) DES and triple antiplatelet therapy reduces the risk of MACCE not only in one monthbut also in one year. statin and DES can reduce mortality in one year after PCI.Acutecoronary syndromes; Major adverse cardiac or cerebral event;(3) Statins, DES, beta blockers, ACEI can reduce mortality in the ACS patients after1year. (4) Hypertension, age, heart function, diabetes patients after PCI respectively on whetherto choose statins, β-blockers, ACEI and DES stents.