Significance Of PET-CT、MRI And VEEG In The Diagnosis Of The Intractable Epilepsy And Presurgical Localization Of Epileptogenic Zones

Objective: To explore the diagnostic value of PET-CT、 MRI、 VEEG andcombination of those tests in the presurgical evaluation of intractable epilepsy.Method: To collecte retrospectively the clinical data of patients withintractable epilepsy in our department from January2010to December2013, suchas clinical symptoms and the result of VEEG、 MRI and PET-CT. After operationpatients were followed up from0.5to2years. According the result of ECoG andEngel grade, evaluate and analysis the presurgical evaluation in localization ofepileptogenic zones among PET-CT、 MRI and VEEG.Results: All19patients underwent MRI and VEEG,6patients underwentPET-CT due to different localization result of VEEG、 MRI and clinical symptomsor the normal MRI. All the patients underwent operations under the guidance ofECoG. The epileptogenic zones were located accurately by combination of VEEG、MRI and clinical symptoms with13patients, by combination of PET-CT、 VEEGand clinical symptoms with4patients, and by combination of PET-CT、 MRI andclinical symptoms with2patients. The Epileptic Engle grade: gradeⅠ in12cases，gradeⅡ in5cases and grade Ⅲ in2cases.Conclusion: VEEG and MRI could be used as the basic presurgicalevaluation test of intractable epilepsy. The value of PET-CT is significant inlocalization of epileptogenic zones when VEEG and MRI have the differentlocalization result.