The Analysis Between The Level Of Ferritin And Correlative Factor Among In Overweight Or Obesity Patients With Type2Diabetes Mellitus

Objective The aim of the present study was to investigate the relationship between thedegree of obesity and ferritin for providing a theoretical basis for the prevention andtreatment of obesity.Methods160cases of type2diabetics hospitalized in Endocrinology Department ofour hospital from June2013to December2013were selected, including34males and26females. According to the Chinese adult overweight and obesity prevention and controlguide（Trial）findings, patients were divided into two groups, Obesity group39patients（21males and18females, BMI≥24kg/m2）, the diabetic group21patients（8malesand13females, BMI<24kg/m2）. All the subject on an empty stomach for more than12hours, no alcohol24hours after early morning pump elbow6ml venous bloodimmediately laboratory detection of fasting levels (SF); fasting plasma glucose (FPG),fasting insulin (FINS); serum total cholesterol (TC), triglyceride (TG) and high-densitylipoprotein cholesterol (HDL-C), glycosylated hemoglobin (HbA1c), according to thecomputation formula insulin resistance index(HOMA-IR)..All data use SPSS19.0statisticalpackage for statistical analysis, all measurement data used by mean±standarddeviation(x±s). Two sets of comparison groups use t test. Counting information areexpressed as percent, Counting material inspection by Chi-Square test. Multiple sampleswere compared with single factor analysis of variance.The correlation between twoindicators is conducted with Pearson. Analysis of multiple variables is conducted withstepwise regression analysis.Result1Gender comparison of between obesity group and diabetic group: Through χ2analysis, the gender constitution of two groups of patients with type2diabetes has nostatistical difference with the control group and through t test, there is no obviousdifference in age, height and course among the two groups, so they are comparable.2Thegeneral data of between obesity group and diabetic group: Comparison of body weight, BMI, SBP,DBP, FPG, FINS, HOMA-IR, HbA1C, TC, TG, the obesity group are higher than diabeticgroup（P<0.05）. Comparison of HDL-C, the diabetic group are higher than the obesitygroup.3. Comparison of he levels of SF between obesity group and diabetic group. thedifference was statistically significant (P<0.05). Obesity group was higher than diabeticgroup. There are23cases of patients with SF>248ng/ml in obesity group,6cases in diabetic group. it indicated that SF are closely linked to obesity Patients With Type2Diabetes Mellitus.4Pearson correlation analysisis was carried out to analyzed therelationship between BMI and Gender, age, SF、FPG、FINS、HOMA-IR、TC、TG、HDL-C、SBP、DBP. BMI has positive correlation with age、SF、FPG、FINS、HOMA-IR、TC、TG、SBP、DBP and has negative correlation with HDL-C,5WithBMI as dependent variable and with courses of disease, SF, HOMA-IR、TG、TC andHDL-C as independent variable, multiple stepwise regression analysis is carried out.HOMA-IR and SF have positive correlation with BMI.（P<0.05）.Conclusion1Comparison of he levels of SF between obesity group and diabetic group,obesity group was higher than diabetic group2.BMI has positive correlation with age、SF、FPG、FINS、HOMA-IR、TC、TG、SBP、DBP and negative correlation withHDL-C.3. A linear relationship among BMI、HOMA-IR and SF.Table7, figure0;Reference102...