Therapeutic Effectiveness On Early Glottic Cancer By Radiofrequency Ablation Treatment

Objective: A retrospective analysis of radiofrequency ablationtreatment of early glottic cancer.Methods: Patients with early glottic cancer in November2009-2014January, Shanghai Jiaotong University Affiliated Sixth People’s Hospital ofShanghai Otolaryngology Head and Neck Surgery,53cases were treated.Patients undergoing radiofrequency ablation in15cases, the CO2laser resection in13cases,25cases of patients with partial laryngectomy. Allpatients Outpatient review with electronic laryngoscope and telephonefollow-up review. Analysis of clinical data comparing the three surgicaloptions with SPSS18.0statistics programs.Results: The average hospital stay of early glottic cancer patients afterradiofrequency ablation treatment was (8.20±2.76) days,after CO2lasertreatment was (9.23±4.02) days (P=0.431), after the treatment of partiallaryngectomy was (19.68±10.14) days (P=0.000and0.001); the meanoperative time of radiofrequency ablation treatment group was (0.92±0.65)h, CO2laser treatment group was (0.72±0.34) h (P=0.320), while thepartial laryngectomy treatment group was (2.61±0.92) h (P=0.000and0.000); CO2laser treatment group’s hospitalization costs less thanradiofrequency ablation treatment group’s (P=0.043), both significantlybetter than partial laryngectomy group; The amount of bleeding duringradiofrequency ablation surgery and the CO2laser surgery was significantlybetter than partial laryngectomy group; the recurrence rate was nosignificant difference between each groups.Conclusions: Radiofrequency ablation treatment of early glottic cancerrecurrence rate, no significant differences respect to the CO2lasertreatment and partial laryngectomy treatment; representing partiallaryngectomy with shorter operative time, less trauma, no tracheotomy,surgery after less complications, higher quality of life after surgery and so on.