Research On Pathological Tremor Mechanism And Assisted Tremor Suppression Techniques

Tremor is a common movement disorders phenomenon, manyresearchers launched a study of its pathogenesis, however, a clear anddefinite understanding has not been achieved. At present, there are twomechanisms about tremor: central tremor and peripheral tremor, andexploring tremor mechanisms from engineering point throughmathematical modeling approach has become a trend. We conducted asimulation to study the two causes of tremor based on the musculoskeletalmode with intrinsic and proprioceptive feedback, and verified thesimulation results via experiments on normal subjects.In addition, assisted tremor suppression technology researchattached the interest of many researchers. Functional Electrical Stimulation(FES) as an emerging technology, has been widely applied in the field ofrehabilitation engineering. if we can apply it in terms of tremorsuppression, there is a huge potential customer base because their systemscan be integrated as cuff style, beautiful, practical, decorative, appearancemore acceptable to patients. In this paper, a simulation is conducted tostudy the one DOF kinetic tremor based on a nonlinear wristmusculoskeletal model, through a high-pass filter to filter out lowfrequency voluntary movements for the wrist tremor signal. Theperformance of the PID and fuzzy logic adaptive PID were compared insingle DOF kinetic tremor suppression. The tremor suppression system ofwrist single DOF is developed under the guidance of simulation results，also the clinical trials were carried out. Finally, the multi-DOF tremorsuppression simulation is conducted, and in this section the wrist skeletal model is similar to the state space in the form of an inverted pendulumequation with coupling characteristics, which can better characterize thetrue characteristics of the human wrist joint. The feedforward controlbased on inverse model is used to improve the real-time response of thesystem, using a linear quadratic regulator (LQR) control algorithm to carryout the elimination of tremor, and the results show that the control strategycan get a better tremor suppression effect.