Analysis Of Clinical Findings In133Patients With Acute Pulmonary Embolism

[Objective] To investigate the clinical value of general information, risk factors, clinical feature and electrocardiogram(ECG) in risk stratification of patients with acute pulmonary embolism(APE).[Method] We performed a retrospective study of133patients who had confirmed APE from May2009to May2012.[Results] There were66females and67males, the age range was29to96years, and the mean age was66.50±14.56. Based on European Society of Cardiology risk stratification,111(83.5%) patients were classified as non-high-risk APE group,22(16.5%) patients as high-risk APE group. A comparison between non-high-risk APE group and high-risk APE group of general information, risk factor and clinical feature indicated that syncope was a common clinical feature in high-risk APE group, the incidence rate was63.6%, and3.6%in non-high-risk group, the difference was statistically significant(p=0.000). A comparison between two groups indicated that the following ECG findings were more common in high-risk APE group:negative T waves in leads Ⅴ1-Ⅴ4, ST segment elevation in leads Ⅲ and Ⅴ1, qR or QR in lead Ⅴ1, the incidence rate were63.6%,40.9%,45.5%and36.4%, respectively, the difference were statistically significant (P=0.002, P=0.018, P=0.034, P=0.006). In multivariate analysis, T waves in leads Ⅴ1-Ⅴ4(OR3.492,95%CI1.266-9.634, P=0.016), qR or QR in lead Ⅴ1(OR3.908,95%CI1.272-12.003, P=0.017) were independent predictors of high-risk PE group.[Conclusions] In our Chinese APE patients, syncope was a common clinical feature in high-risk APE group, T waves in leads Ⅴ1-Ⅴ4, qR or QR in lead Ⅴ1were independent predictors of high-risk APE group. Our study concludes that ECG analysis may be a useful method for risk stratification of patients with APE.