Objective:to study the mean platelet volume (MPV)GRACE score in acute ST segment elevation myocardial infarction(STEMI) treated with emergency coronary artery stent implantation(PCI) patients during the period of school, and the value of evaluation outcome at6months.Methods:continuous selected between September2011and June2011hospitalized patients with STEMI and accept emergency PCI as STEMI group,102cases of coronary angiography ruled out202cases of coronary heart disease(CHD) admitted to hospital patients as control group, all patients admitted to hospital immediately accepted routine blood, troponin I, creatine kinase-KB and electrocardiogram examination, GRACE score calculation. Observation of STEMI patients in hospital and6months follow-up period of major adverse cardiac events(MACE) and the correlation of MPV and GRACE score on admission.Results:the group STEMI MPV is higher than the control group (P<0.001). MACE group of MPV, GRACE score, Gensini score were higher than MACE group did not occur. MPV, GRACE admission score and two variables to predict the MACE of area under the ROC curve (AUC) were0.713(95%CI,0.453to0.973, P=0.042),0.850(95%CI,0.678to1.0, P=0.002),0.946(95%CI,0.862to1.0, P=0.000).MPV, GRACE hospital ratings and two variables to predict before6months of MACE area under the ROC curve (AUC) were0.695(95%CI,0.474to0.917, P=0.044),0.72(95%CI,0.566to0.885, P=0.02),0.742(95%CI,0.561to0.923, P=0.013). Kaplan and Meier survival analysis showed that followed up to six months, the high MPV group had a significantly higher incidence of MACE low MPV group (21.7%vs5.4%, P=0.032; LogRank=4.272, P=0.039). GRACE score high-risk group had a significantly higher incidence of MACE low-risk group (16.6%vs3.6%, P=0.037; LogRank=3.934, P=0.047).Conclusion:the high MPV for STEMI patients in hospital and the hospital for six months the occurrence of adverse events with good predictive value, MPV with GRACE scores can be used to judge the STEMI high-risk groups. |