High Blood Pressure Patients Microalbuminuria And Allergic C-reactive Protein And Lower Limbs Hardening Of The Arteries Relationship

Objective:To determine the microalbuminuria, C-reactive protein and ankle brachial index in hypertension patients. We want to explore the relation between microalbuminuria and lower extremity arteriosclerotic and the value of microalbuminuria on assessment of the cardiovascular risk in hypertension patients.Methods:350primary hypertension patients in our hospital were included. According to combination with microalbuminuria, the hypertension patients were divided into two groups, one was microalbuminuria group, the other was none microalbuminuria group. There were193patients in microalbuminuria group, including117male and76female aged54.3±5.8. There were157patients in none microalbuminuria group, including90male and67female aged54.3±5.8. History, cholesterol, blood sugar, uric acid, creatinine, C-reactive protein and ankle brachial index were measured. The differences of clinical index and the risk factors of microalbuminuria in two groups were analyzed.Results:The course of disease was longer in microalbuminuria group than that in none microalbuminuria group. The pulse pressure was significantly increased in microalbuminuria group. LDL-C and creatinine were heighted n microalbuminuria group than those in none microalbuminuria group. The high-sensitive C reactive protein of the patients in microalbuminuria group was much higher and the ankle brachial index was much lower than the patients in non microalbuminuria group. The result of Pearson association analysis showed that ankle brachial index was negative correlated with high-sensitive C reactive protein. The course of disease, ankle brachial index, pulse pressure, high-sensitive C reactive protein and creatinine were the risk factors of microalbuminuria.Conclusions:Microalbuminuria was associated with lower extremity arteriosclerotic. Microalbuminuria and ankle brachial index screening were useful for sub-clinical arteriosclerosis patients.