| PART IA SURVEY ABOUT SERUM VITAMIN A STATUS INADMITTED NEONATESObjective：To observe the serum vitamin A(VA) status in admittedneonates，and compare the average level of VA between preterm infantsand full-term infants. Comparing the average level of VA of preterminfants in different gestational ages and birth weights.Method:213infants admitted to our neonatal department wereenrolled in our study. We measured the serum concentrations of VA,According to gestational weeks, we divided these infants into pretermgroup and full-term group. And then the difference between two groupswere observed. According the the gestational ages, we divided the preterminfants into early preterm infants, moderate preterm infants and latepreterm infants, then differences in every2groups were examined. According to the birth weight, we divided the preterm infants into very lowbirth weight, low birth weight and normal birth weight, and also comparedthe differences in every2groups.Results：(1)84of the total study subjects (39.44%) were classifiedinto vitamin A deficiency(VAD)，119of the total study subjects (55.87％)were presented with sub-clinical vitamin A deficiency(SVAD), and the restof all (4.69%) were normal;(2) The serum concentrations of VA in thepreterm group were lower than full-term group, but without any significantdifference (P＞0.05);(3) the early preterm infants presented the lowestserum concentrations of VA compared with the moderate and late preterminfants, but the differences were not statistically significant (all the P valuein every two group were＞0.05);(4) the very low birth weight infantspresented the lowest serum concentrations of VA compared with the lowand normal birth weight infants without significant differences (all the Pvalue in every two group were＞0.05).Conclusion：(1) Infants in this study were at high risk of VAD.(2)early preterm infants and low birth weight infants presented the lowestserum concentrations of VA, but the relationship between serumconcentration of VA and gestational ages or birth weight was uncertain, thefurther study are warranted. PART ⅡTHE CORRELATION BETWEEM SERUM VITAMIN ASTATUS AND NEONATAL RESPIRATORY DISTRESSSYNDROMEObjective：To observe is there any relationship between serum VAstatus and prevalence of NRDS, and is there any correlation between serumconcentration of VA and the severity of NRDS.Method:166preterm infants admitted to our neonatal departmentwere regarded as our study subjects. We measured the serumconcentrations of vitamin A, and compared the prevalence of NRDS atdifferent levels of VA. According to the clinical manifestation and X-rays,we divided them into NRDS group and non-NRDS group, and selected30patients randomly from non-NRDS group as controlled group according tothe gestational ages, then the difference between NRDS group andcontrolled group were observed. And we divided the30NRDS patientsinto mild group (including satgeⅠandⅡ) and severe group (includingstage Ⅲ and Ⅳ) according to the description of the chest X-ray, then thedifference between the2groups were observed.Results：(1)Among166preterm infants, when serum concentration ofVA were lower than0.35μmol/L, the prevalence of NRDS were21.54%, when serum concentration of VAranges from0.35μmol/L to0.7μmol/L, theprevalence of NRDS were16.13%, when serum concentration of VA higherthan0.7μmol/L, the prevalence of NRDS were12.50%, but the differencebetween every two groups were not significant(P＞0.05);(2)Whengestational ages ranges from34weeks to37weeks, the serumconcentrations of vitamin A of NRDS group were lower than controlledgroup, with a significant difference (P＜0.05);(3) among30NRDS infants,the serum concentrations of vitamin A of sever group was lower than mildgroup, but with out any significant difference(P＞0.05).Conclusion：(1)The serum level of late preterm infants suffering fromNRDS (34w≤GA <37w) were lower than those with the same gestationalweeks but without NRDS.(2)The relationship between serum VAconcentration and the prevalence of NRDS should be investigated further. |
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