Analytical Investigation Of Onset Time And Main Clinical Features Of Superior Sagittal Sinus Thrombosis During Pregnancy And Puerperium

Objective:To analyze onset time and clinical features of superior sagittal sinus thrombosis during pregnancy and puerperium so as to provide the evidence for its early diagnosis and treatment.Materior and Methods:The clinical features of superior sagittal sinus thrombosis as well as imaging examination results of243cases of superior sagittal sinus thrombosis in the people’s Republic of China, indexed from Chinese periodical full text databases(http://www.edu.cnki) and in our hospital from2002-2013, were analyzed according to three stages:pre-natal, labor and post-natal.Results:In pre-natal and labor stage, patients with superior sagittal sinus thrombosis were attacked in an acute fashion, its rate of misrecognition and mortality up to70%and60%.The proportion of superior sagittal sinus thrombosis in the mentioned stage were2.9%and1.2%,respectively.And all patients had symptoms of intracranial hypertension,85.7%and100%with twitches,71.4%and66.7%with conscious disturbance,57.1%and33.3%with paralysis, respectively. But in post-natal stage, its showing subacute or acute fashion, the rate of improper diagnosis and mortality were2.6%and7.3%, respectively. The proportion of superior sagittal sinus thrombosis in post-natal stage reached to95.9%in all patients, and the incidence of the four kinds of clinical features mentioned above were87.6%,53.6%,43.8%and45.9%, respectively. The positive rates of graphical changes were33.3%and100%by the inspection of computerized tomography and magnetic resonance imaging/magnetic resonance venography, respectively.Conclusions:The women in early puerperium are susceptible to superior sagittal sinus thrombosis compared with the other periods. The situation of patients with superior sagittal sinus thrombosis in pre-natal and labor stage were deteriorated speedily with high rate of misrecoagnition and mortality. The patients who were doubtful to superior sagittal sinus thrombosis in pre-natal and labor stage should be diagnosed by MRI/MRV inspection and treated correctly as soon as possible...