Comparative Analysis Of Treatment Outcomes And Complication Risk Rates Of Cervix Cancer On FIGO StageⅠB-ⅡA In Xinjiang District After The Four Different Treatment Modals

Objective:To compare treatment outcomes and the complication risk rates of FIGO stage IB-IIA cervix cancer in Xinjiang district.Methods:The survival rate was calculated by Kaplan-Meier method and the difference was compared by Log-rank test. Multivariate analysis was performed using Cox regression model.Results:The3-years and5-years survival rates were82.8%,79.3%, the5-years survival rates of bulky tumors and non bulky tumors were71.2%,88.9%(.P=0.008). Univariate analysis showed that clinical stage,nation,tumor size,degrees of differentiation and postoperative risk factor impact on5-years survival rates were important (P<0.05).Multivariate analysis showed that clinical stage, tumor size, degrees of differentiation,postoperative risk factor were independent prognostic factors for cervical cancer (P<0.05). The5years overall survival rates of different treatment modals as operation, radical radiotherapy,preoperative intracavitery after loading radiotherapy±chemotherapy (preoperative treatment) and postoperative chemoradiotherapy (postoperativetreatment) were80.9%,82.5%,78.8%,72.4%(P=0.593) respectively. The four different treatmenr groups compare each other show that5-years survival rates and complication were resemble.The5-years survival rates of bulky cervical cancer of the operation group and the preoperative treatment group were48.0%,78.8%(P=0.015),and also the rates of postoperative risk factor of these two groups were66.7%,16.0%respectively(P=0.000).Conclusions:The prognosis were intimate related to clinical stage, tumor size, degrees of differentiation and postoperative risk factor. preoperative after-loading radiotherapy±chemotherapy can reduce postoperative risk factor rate and greatly increase survival rate of bulky cervix cancer on FIGO stage IB-IIA.Conduce to decrease portion of the postoperative adjuvant therapy and also the treatment fees.Suggest that concurrent chemoradiotherapy as first choice for bulky cervical cancer on stage IB-IIA,choose other treatment models as preoperative treatment precisely and individually,refrain from the double whammy of the blind combination of two main local therapy methods.