The Surgical Treatment Of Focal Ground-glass Opacity In The Lung

Objective: To explore and summarize the experience of the surgicaltreatment of focal ground-glass opacity in the lung.Methods: From March2008to March2013,31cases of focalground-glass opacity were collected from the department of cardiothoracicsurgery, the first affiliated hospital of ChongQing medical university.31patients were12males and19females, aged52.10±9.58years old. All thepatients were examined by HRCT preoperatively. There were10cases inthe left upper lobe of the lung,4cases in the left lower lobe,12cases in theright upper lobe,2cases in the right middle lobe,3cases in the right lowerlobe. There were6cases of open surgery and25cases of video-assistedthoracoscopic surgery (VATS). The postoperative pathologic results were4cases(12.9%) of benign lesions and5cases(16.13%) of atypicaladenomatous hyperplasia(AAH), adenocarcinoma in9cases(29.03%),bronchioloalveolar carcinoma(BAC) in13patients(41.94%). The operationmethod was to location the focal ground-glass opacity prior to surgery,then wedge resection was performed. And then the pathologist examined it,if it was benign, then the end; But if it was malignant, the lobectomy andlymphadenectomy or wedge resection only were decided. Results: All the patients underwent surgical treatment, which included10cases of wedge resection and21cases of lobectomy andlymphadenectomy. The operative time was148.90±63.10min,the amount ofbleeding loss was166.13±98.27ml, the number of lymph node dissectionwere4.32±2.87, the postoperative ICU stay was2.26±0.82d, and thehospital stays were9.45±2.98d。All the patients were discharged safely,except the VATS group had one case of pulmonary leakage, but wasimproved and discharged after conservative treatment. There weresignificant difference in the amount of bleeding and hospitalization time(P＜0.05) between. The diameter of malignant fGGO was significantly largerthan benign fGGO(P＜0.05).Conclusion: It’s believed that the focal ground-glass opacity is inclose relation with the early stage of lung cancer. And minimally invasivesurgery should be preferred, but further research was needed as for surgicalapproach and Lymphadenectomy, and so on.