| Objective: To investigate iodine nutrition and thyroid autoantibodies inpregnancy and their relation to thyroid function.Methods: Electrochemiluminescence method for the determination ofthyroid function and thyroid autoantibodies of140pregnancies，dependingon the thyroid function, which are divided into two groups, thenormals(n=117) and the subclinical hypothyroids(n=23). Apply arseniccerium catalytic spectrophotometric method to determine the content ofthe pregnancies’ urine specimens. Investigate the awareness of thyroiddisease history among the thyroid dysfunctions.Result:①The prevalence of iodine deficiency is50%and57%in thenormal group and the subclinical hypothyroid group, respectively.②Thestate of iodine level is not related to thyroid function.③The level ofserum TPOAb and TgAb is markedly related to serum TSH, so is the levelof serum TPOAb related to serum FT4.④Among the subclinicalhypothyroids,70%didn’t screening thyroid function and thyroidautoantibodies before pregnancy,8.7%denies the thyroid disease history, 21.7%suffer from hypothyroidism before pregnancy.Conclusion: We advocate the screening of urine iodine and thyroidautoantibodies before or at the first trimester of pregnancy, aiming tocorrect iodine deficiency and preventing supplementing too much iodineelement, at last improving the outcome of perinatal stage and decreasingthe negative effect on the offsprings. |
