The Study Of Clinical Application Of Nephron Sparing Surgery With Don’t Block Renal Artery For Localized Renal Cell Carcinoma

ObjectiveBy comparing the study of does not block the renal artery nephron-sparingsurgery and conventional renal artery blocked nephron sparing surgery for renal cellcarcinoma, to evaluate the safety and efficacy of nephron sparing surgery with don’tblock renal artery.MethodsWe retrospective analysis84patients who underwent nephron sparing surgeryin Affiliated Tumor Hospital of Zhengzhou University,from April2012-December2013. Among them,41patients underwent does not block the renal arterynephron-sparing surgery(study group),the other43patients unserwent conventionalrenal artery blocked nephron sparing surgery(control group). Size of tumor,operativetime, estimated blood loss, surgical margin negative rate,postoperative day1drainage,postoperative hospital stay, complications,pre-operative and post operativecreatinine，pre-operative and post operative renal glomerular filtration rate werecompared between two groups. data were analyzed by SPSS17.0software. ResultsAll surgeries were successfully accomplished.There were no significantdifferences between two groups in average tumor mean size (2.8±0.7cm vs3.0±0.6cm, respectively,P>0.05).There were no significant differences between twogroups in averag inoperative time(141.5±29.6min vs132.7±30.1min,respectively,P>0.05). There were significant differences between two groups in averag estimatedblood loss(289.5±86.5ml vs97.5±33.5ml,respectively,P<0.05).There were nosignificant differences between two groups in averag postoperative day1drainage(197.75±13.6ml vs201.3±12.2ml,respectively,P>0.05).There were nosignificant differences between two groups in postoperative hospital stay(9.0±0.8dvs9.1±0.9d,respectively, P>0.05).There were no significant differences between twogroups in the mean serum creatinine before NSS(65.40±11.90μmol/L vs64.24±8.64μmol/L,respectively, P>0.05).There were significant differences betweentwo groups in1week after NSS(88.40±8.47μmol/L vs105.43±9.33μmol/L,respectively,P<0.05).There were no significant differences between two groups in6months after NSS(67.35±9.69μmol/L vs65.48±7.31μmol/L,respectively,P>0.05).There were no significant differences between two groups in the GFR in operate sidebefore NSS(52.61±6.22ml/min vs51.29±3.99ml/min,respectively,P>0.05).Therewere significant differences between two groups in the GFR in operate side3months after NSS(46.59±6.19ml/min vs35.45±3.77ml/min,respectively,P<0.05).There were significant differences between two groups in the GFR in operate side6months after NSS(48.42±6.07ml/min vs37.72±3.67ml/min,respectively,P<0.05).There were no recurrence or death patients in followed,and renal function is normalduring the follow up.ConclusionsThe nephron-sparing surgery with don’t block renal artery is a promotion of theoperation, but it need to choose the right disease.