Study On Risk Factors And Predicting CRP’s Value Of Gestational Diabetes Mellitus Under The New Diagnostic Criteria

Objective: The purpose of this survey is to investigate the relativity between risk factorsand inflammatory cytokins of C-reactive protein (C-reactive protein, CRP) under thenew diagnostic standard.It provide evidence-based evidence for early prevent of riskfactors of GDM, prevention of GDM and longterm compications.From the cure not illthe guiding ideology of TCM,to provide reference for structuring perinatal care modelcreated with TCM feature.Methods: Cross session study method is used for this research.this research carry on asampling survey among the singletons of pregnant women who pregnant within28weeksthat underwent regular perinatal care in first affiliated hospital of Henan University ofTraditional Chinese Medicine from April2013to February2014.Detecting GRP before firsttime Perinatal Health Care. Selecting91cases of pregnant women with GDM diagnosisstandard as observation group, and using simple random sampling method is chosen fromamong179completed questionnaires during the same period among the health care of91cases of healthy pregnant women as control group. To investigate the selected pregnantwomen with GDM epidemiological questionnaire (see Appendix1), record the results,andtype into the SPSS and to establish the database. The χ2test is used for the count data usingSPSS18.0statistics software,the t test is used for measurement data, Single sample k-s testis first used for measurement data to test its distribution is normal distribution.if it is normaldistribution,two independent sample t test is used for statistical analysis,if it dose not belongto the normal distribution,two independent sample nonparametric test is used for statisticalanalysis.Results:①O bservation group and control group, these2groups have obvious statisticsdifference (P＜0.05) in below aspects: diet partial addicted,weight before pregnant, currentpregnant age, first time pregnant age, weight increasing when OGTT, diabetes history offamily, the history of GDM, the histories of abnormal pregnant, times of gestation, huge newborn, the histories of amniotic fluid delivery, the histories of polycystic oophoron symptom,The pregnancy with fetal huger than gestational age or amniotic fluid pregnancy. ②O bservation group and control group, these2groups have obvious statistics difference (P＜0.05) in CRP level.③After compare between observation group and control group,difference don’t have statistics significance (P>0.05) with below aspects: occupation,education degree, delivery times, delivery methods, hepatitis b virus surface antigen,the histories of repetitive candida infection.④After multi-factor Logistic regressionanalysis,these7dangerous factors are categorized as regression model, which areweight before pregnant, pregnant age, times of gestation, the histories of abnormal pregnant,huge new born, the histories of amniotic fluid delivery, the histories of polycystic oophoronsymptom,CRP. Regression coefficient individually are1.334,0.520,-0.813,1.580,1.709,1.513,0.262.Conclusions:①Logistic regression result reveals that below6are independent dangerousfactors of GDM under new diagnostic standard, which are weight before pregnant, pregnantage, the histories of abnormal pregnant, huge new born, the histories of amniotic fluiddelivery,the histories of polycystic oophoron symptom.②CRP level and the risk ofdeveloping new diagnostic criteria for GDM was a positive correlation,there are certainearly prediction effect.③The factors such as diet partial addicted,the age of first pregnant,the histories of GDM, diabetes history of family,current pregnancy with fetal huger thangestational age or amniotic fluid pregnancy, was not included regression model, might be themixed factors which causing GDM.