Clinical Analysis Of Severe Acute Renal Failure

Objective:To explor the pathogenic and prognostic factors in patients with severe acute renal failure (sARF).Methods:A total of54cases with severe ARF patients were enrolled from hospitalized in our hospital from January2008through2012January. All patients were divided into two groups,young and middle-aged group (less than60aged, n=28) and an elderly group (more than60aged, n=26). Meanwhile, the pathogenic factors, biochemical criteria (BUN, Scr and ALB),therapeutic methods and prognostic factors were analyized in two groups with severe ARF patients.Results:The main pathogeng of sARF is toxicosis,followed by cardiovascular disease.The incidence of sARF was similar between young and middle-aged (<60age, n=28) and elderly groups(51.9%.48.1%).The main pathogenic factors in young and middle group was toxicosis, and was cardiovascular disease in elderly groups.The main therapeutic methods was renal replacement therapy(RRT,66.7%) and pharma-cotherapy(33.3%).The albumin was more than37g/L and lower than37g/l was29.63%and70.37%in preteartment of all sARF patients,and the mortality was18.75%and47.37%between two groups,there were significant differences between two groups (P <0.05).The mortality was46.40%and19.20%in young and middle and elderly groups,respectively,there were significant differences between two groups (P<0.05)Conclusion:The main pathogeng of sARF is toxicosis,followed by cardiovascular disease.The prognosis of patients with sARF may was correlated with the pathogenic factors,ages,degree of disease severe, therapeutic methods and nutrition condition.